Global Acute Malnutrition (GAM) Clinical Trial
Official title:
Effectiveness of an Integrated Treatment Protocol for Acute Malnutrition: A Non Inferiority Trial in Passore Province (Northern Region), Burkina Faso
MUAC only is a pilot trial external control carried out between January 2017 and December
2017 in the Yako district (northern region), Burkina Faso.
The objective of this study is to evaluate an integrated protocol for acute malnourished
children without medical complication. The hypotheses of the integrated protocol include :
1. A global treatment of acute malnutrition (moderate and severe) with a single treatment
(RUTF) would improve the functioning of the program through early identification of
acutely malnourished children, while achieving a better coverage and using a single
supply chain.
2. A gradual reduction of RUTF dosage according to a child's MUAC status could
significantly increase the number of children on treatment without increasing overall
RUTF quantity while maintaining similar recovery rates.
Objectives :
Main objective :
To ensure the recovery rate of the integrated protocol for treatment of acute malnutrition is
significantly greater than 75% (reference value of the national program in BF).
Secondary objectives :
- To ensure the mortality rate of the integrated protocol for treatment of acute
malnutrition is significantly lower than 3% (reference value of the national BF
program).
- To ensure the default rate of the integrated protocol for treatment of acute
malnutrition is significantly lower than 15% (reference value of the national BF
program).
- To ensure the non-response rate of the integrated protocol for treatment of acute
malnutrition is significantly lower than 8%.
- To ensure the hospitalization rate of the integrated protocol for treatment of acute
malnutrition is significantly lower than 15%.
- To ensure the coverage rate of the program increases by 30% after the year the
integrated protocol was introduced (specific protocol annexed).
- To estimate the relapse rate of the integrated protocol for treatment of acute
malnutrition.
- To compare RUTF rations per child of the integrated protocol compared to the national
protocol
Methods :
The study population will include all acutely malnourished children aged between 6 and 59
months seeking consultations at all of the health centers in Yako District between January
2017 and December 2017.
The study will be implemented in Burkina Faso's Yako District, which includes 54 health
centers.
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