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NCT04719806 Clinical Trial

MR Textural Analysis in Low Grade Gliomas

Glioma Clinical Trial

Official title:
Textural Analysis in Low Grade Gliomas on Pre Operative MRI Exams to Determine Molecular Status : a Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04719806
Other study ID # 20radio01
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2010
Est. completion date May 1, 2019

Study information
Verified date January 2021
Source Centre Hospitalier Universitaire de Nice
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

WHO classification of low grade gliomas now relies on tumoral molecular patterns, especially on IDH mutation and 1p/19q co deletion status. Textural analysis on medical imaging is studied in several fields, and could provide help in patients with brain tumor due to possible complications of brain biopsy. The purpose of this study is to determine if specific textural signature on MR imaging could be found for low grade gliomas. The investigators included patients with LGG diagnosed at CHU of Nice abd whose first MRI was available on the PACS of the CHU. Textural data are extraxted by tumoral contouring and specific logiciel (LifeX) and histopathologic data are assessed for each patient. Then the investigators analyze it to dtermine if textural indices can predict molecar status.

Recruitment information / eligibility
Status Completed
Enrollment 80
Est. completion date May 1, 2019
Est. primary completion date May 1, 2019
Accepts healthy volunteers No
Gender All
Age group 19 Years to 77 Years
Eligibility Inclusion Criteria: LGG diagnosed at CHU of Nice abd whose first MRI was available on the PACS of the CHU Exclusion Criteria: -

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France Nice University Hospital Nice

Sponsors (1)
Lead Sponsor Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary review of MRI images to find clues that can predict molecular status 9 years
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