Glioma Clinical Trial
Official title:
Survival Significance and Clinical Characteristics of Molecular Pathology and Genetic Variation in Brain Gliomas
NCT number | NCT04216537 |
Other study ID # | GiomaMG-1 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | January 1, 2018 |
Est. completion date | June 1, 2025 |
This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology and genetic data. This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Status | Recruiting |
Enrollment | 3000 |
Est. completion date | June 1, 2025 |
Est. primary completion date | January 1, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 1 Year to 95 Years |
Eligibility | Inclusion Criteria: - Patients must have radiologically and histologically confirmed diagnosis of primary glioma - Life expectancy of greater than 3 months - Must receive tumor resection - Must have sufficient fresh frozen tissues for NGS - Signed informed consent Exclusion Criteria: - No gliomas - No sufficient amount of tumor tissues for detection of molecular pathology - Patients who are pregnant or breast feeding - Patients who are suffered from severe systematic malfunctions - Do not have sufficient fresh frozen tissues for NGS |
Country | Name | City | State |
---|---|---|---|
China | Department of Neurosurgery, First Affiliated Hospital of Zhengzhou University | Zhengzhou | Henan |
Lead Sponsor | Collaborator |
---|---|
The First Affiliated Hospital of Zhengzhou University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Overall Survival (OS) | The length of time from enrollment until the time of death (OS, overall survival) | From enrollment to death of patients. Estimated about 5 years. |
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