Glioma, Malignant Clinical Trial
Official title:
The Combination of Hypofractionated Stereotactic Radiotherapy and Chemoradiotherapy Using Intensity-Modulated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme: A Prospective, Single-Center, Single-Arm Phase II Clinical Trial
This study aims to evaluate the safety and effectiveness of the combination of 30Gy/5fx HSRT and 20Gy/10fx IMRT adjuvant therapy. The total biological effective dose (BED) of the PTV is 72 Gy in a ratio of alpha/beta ratio of 3, which equals to the conventional 60Gy/30fx treatment. This study can provide evidence for future non-inferiority phase III randomized controlled trials. The abbreviated course of radiotherapy can reduce the treatment time by half, benefit patients, and utilize the health resource.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
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| Completed |
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Phase 1/Phase 2 | |
| Recruiting |
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Phase 1/Phase 2 | |
| Active, not recruiting |
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| Recruiting |
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N/A | |
| Recruiting |
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Mapping of Tumor Stem Cells in the Resection Marigin During Extirpation of Highly Malignant Gliomas Using GlioStem
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| Recruiting |
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Niraparib In Recurrent IDH 1/2 Gliomas
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Early Phase 1 | |
| Recruiting |
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Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG
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Early Phase 1 | |
| Active, not recruiting |
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Phase 1 | |
| Completed |
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| Completed |
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| Recruiting |
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Early Phase 1 | |
| Recruiting |
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N/A | |
| Completed |
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Phase 1 |