Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Status Recruiting

Clinical Trial Summary

This is a single-center, open-label, dose-escalating Phase 0 trial that will enroll participants with a confirmed diagnosed recurrent high-grade glioma (grade 3 or 4 per WHO criteria) targeting the mTOR pathway. Eligible participants will be administered a single infusion of temsirolimus through super-selective intra-arterial infusion or intravenous infusion. Participants will receive the study drug administration on the same day as the planned surgical resection of the tumor.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05773326
Study type	Interventional
Source	St. Joseph's Hospital and Medical Center, Phoenix
Contact	Phase 0 Navigator
Phone	602-406-8605
Email	research@ivybraintumorcenter.org
Status	Recruiting
Phase	Early Phase 1
Start date	May 15, 2023
Completion date	April 30, 2026

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