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Clinical Trial Summary

This is an open-label, single-center Phase 0/1b study that will enroll at least 14 participants with recurrent glioblastoma requiring re-radiation. The trial will be composed of a Phase 0 component (subdivided into Arm A and Arm B), and an expansion Phase 1b. Patients with tumors demonstrating a positive PK response in the Phase 0 component of the study will graduate to an expansion phase that combines therapeutic dosing of AZD1390 plus standard-of-care fractionated radiotherapy (RT).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05182905
Study type Interventional
Source St. Joseph's Hospital and Medical Center, Phoenix
Contact Phase 0 Navigator
Phone 602-406-8605
Email [email protected]
Status Not yet recruiting
Phase Early Phase 1
Start date January 2022
Completion date January 2025

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