Memantine for Recurrent Glioblastoma

Status Terminated

Clinical Trial Summary

The purpose of this study is to determine if a medication called memantine is effective in treating glioblastoma. Memantine targets a specific receptor, called a glutamate receptor, which is thought to be involved in the growth of brain tumors. It has previously been studied for other types of conditions, such as Alzheimer's disease, but it has not yet been evaluated in the treatment of brain tumors. The investigators will also be determining how common it is for patients with brain tumors to have side effects to memantine. Memantine will be taken by mouth twice a day.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Glioblastoma

Clinical Trial Details

NCT number	NCT01260467
Study type	Interventional
Source	University of Rochester
Contact
Status	Terminated
Phase	Phase 2
Start date	November 2010
Completion date	April 2014

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