Glioblastoma Clinical Trial
Official title:
Combined Approach to GBM-resection by 5-ALA and Intraoperative MRI
In the treatment of glioblastoma (GBM) neurosurgical resection of the tumor is usually
considered a a first step of effective therapy. Radical resection of the tumor is highly
beneficial to the patient as measured in progression-free survival and overall survival. At
the same time eloquent areas of the brain have to remain intact to preserve quality of life.
Both 5-ALA fluorescence and intraoperative MRI are used for intraoperative marking of tumor
tissue and thereby to improve precision of GBM-Resection.
We now study whether the combination of 5-ALA fluorescence and intraoperative MRI increases
the number of sites where tumor tissue can be detected.
- Trial with surgical intervention
Precision of GBM-Resection Intraoperative marking of tumor tissue Combination of 5-ALA fluorescence and intraoperative MRI ;
Observational Model: Case Control, Time Perspective: Prospective
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