Metabolic Tumor Volumes in Radiation Treatment of Primary Brain Tumors

Status Completed

Clinical Trial Summary

- Metabolic Tumor Volume (MTV), identified by Magnetic Resonance Spectroscopic Imaging (MRSI) is different from the Clinical Target Volume (CTV) used for radiation dose delivery in the treatment of brain tumors.

- If MTV > CTV, the investigators hypothesize that the difference in volumes (cc) is related to worse clinical outcome. Furthermore, in case of local recurrence, the lesion is located in the MTV area that is outside of the CTV.

- Alternatively, if CTV > MTV, then the difference in volumes is related to higher treatment toxicity.

Clinical Trial Description

Metabolic Tumor Volume (MTV), identified by Magnetic Resonance Spectroscopic Imaging (MRSI) is different from the Clinical Target Volume (CTV) used for radiation dose delivery in the treatment of brain tumors.

- If MTV > CTV, the investigators hypothesize that the difference in volumes (cc) is related to worse clinical outcome. Furthermore, in case of local recurrence, the lesion is located in the MTV area that is outside of the CTV.

- Alternatively, if CTV > MTV, then the difference in volumes is related to higher treatment toxicity. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02006563
Study type	Observational
Source	University of Miami
Contact
Status	Completed
Phase	N/A
Start date	June 8, 2011
Completion date	July 2017

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