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NOA-12: BIBF1120 and R-RT in Glioblastoma

Glioblastoma Multiforme Clinical Trial

Official title:
A Phase I/II, Randomized, Open-label, Multi-centre Study of BIBF1120 + Reirradiation (R-RT) Versus Reirradiation in the Treatment of Patients With First or Second Progression of Glioblastoma

Clinical Trial Summary

Patients with glioblastoma at first or second progression who have failed standard treatment that must have included radiochemotherapy with temozolomide and who are a candidate for a reirradiation can be included into the trial. In the phase I part the minimal tolerated dose (MTD)of BIBF 1120 in combination with radiotherapy will be investigated. Subjects in phase II will be randomised to receive reirradiation alone or reirradiation + 2 x MTD BIBF1120.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01666600
Study type Interventional
Source University Hospital Heidelberg
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date August 2012
Completion date September 2017
View Details
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