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Clinical Trial Details — Status: Terminated

Administrative data

NCT number NCT00589095
Other study ID # 0606001531
Secondary ID
Status Terminated
Phase N/A
First received January 2, 2008
Last updated July 1, 2014
Start date November 2006
Est. completion date August 2011

Study information

Verified date July 2014
Source Yale University
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Observational

Clinical Trial Summary

The purpose of this study is to determine whether dynamic contrast enhanced MRI (DCE MRI) and high diffusion weighting MRI may be used to distinguish between favorable and unfavorable responses to therapy of glioblastoma multiforme. Imaging data will be correlated with histopathologic findings and clinical responses to radiation therapy with or without chemotherapy.


Recruitment information / eligibility

Status Terminated
Enrollment 5
Est. completion date August 2011
Est. primary completion date August 2011
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- The presence of a primary brain tumor that cannot be completely resected that requires radiation therapy with or without chemotherapy.

Exclusion Criteria:

- Patients who do not have a primary brain tumor or who are unable to tolerate the environment of the MRI scanner

Study Design

Observational Model: Case-Only, Time Perspective: Prospective


Related Conditions & MeSH terms


Intervention

Other:
dynamic contrast enhanced magnetic resonance imaging
dynamic contrast enhanced MRI using contrast agent gadodiamide

Locations

Country Name City State
United States Yale University School of Medicine New Haven Connecticut

Sponsors (1)

Lead Sponsor Collaborator
Yale University

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Primary To detect the early "local" treatment responses from the physician recognized GBM "gross tumor volume" (GTV) Upon completion of study No
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