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Multi Peptide Vaccination With XS15 in Addition to Standard Postoperative Radiation Therapy and Temozolomide Chemotherapy in Newly Diagnosed Glioblastoma — GLIO-XS15  

Glioblastoma Multiforme of Brain Clinical Trial

Official title:
Multi Peptide Vaccination With Pam3Cys-GDPKHPKSF (XS15) as an Immunomodulator in Addition to Standard Postoperative Radiation Therapy and Temozolomide Chemotherapy in Newly Diagnosed HLA-A2-positive MGMT-methylated Glioblastoma

Clinical Trial Summary

Newly diagnosed HLA-A2-positive MGMT-methylated glioblastoma patients will be vaccinated with a Multi peptide vaccination with Pam3Cys-GDPKHPKSF (XS15) as an immunomodulator in addition to standard postoperative radiation therapy and temozolomide chemotherapy to assess immunogenicity, efficacy, safety of the combination of multipeptide vaccination and the immune modulator XS15 emulsified in Montanide ISA 51 VG

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04842513
Study type Interventional
Source University Hospital Tuebingen
Contact Ghazaleh Tabatabai, Prof
Phone +497071/29-83269
Email ghazaleh.tabatabai@uni-tuebingen.de
Status Recruiting
Phase Phase 1
Start date May 3, 2021
Completion date August 3, 2025
View Details
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