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NT-501 CNTF Implant for Glaucoma: Safety, Neuroprotection and Neuroenhancement

Glaucoma, Primary Open Angle Clinical Trial

Official title:
CNTF Cell Implants For Glaucoma: A Phase I Study

Clinical Trial Summary

Ciliary Neurotrophic Factor (CNTF) has been demonstrated in multiple pre-clinical models to enhance survival and regeneration of retinal ganglion cells, the retinal neurons injured in diseases like glaucoma. We hypothesize that CNTF delivery to the human eye will provide neuroprotection (prevent loss of vision) and neuroenhancement (improve vision indices) in glaucoma. Patients in the trial will receive an NT-501 CNTF implant (made by Neurotech) into one eye, and will be carefully followed to evaluate safety and efficacy.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01408472
Study type Interventional
Source Stanford University
Contact
Status Completed
Phase Phase 1
Start date April 2011
Completion date October 2014
View Details
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