Optic Nerve Head Strain as Biomarker for Glaucoma

Status Not yet recruiting

Clinical Trial Summary

The investigators will test the hypothesis that images of the optic nerve head taken a 2 different eye pressures will yield strain estimates that are predictive of the course of glaucoma.

Clinical Trial Description

Existing glaucoma patients and suitable control adults will be imaged with an FDA-approved optical coherence tomography instrument. Those who are imaged at 2 different eye pressures will generate biomechanical strain estimates. These will be compared to visual field and retinal nerve fiber layer measurements over time. The investigators expect that baseline strain and their changes over time will be associated with progression rate of glaucoma damage, providing a biomarker for susceptibility. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06240312
Study type	Interventional
Source	Johns Hopkins University
Contact	Harry A Quigley
Phone	4437427079
Email	hquigley@jhmi.edu
Status	Not yet recruiting
Phase	N/A
Start date	July 1, 2024
Completion date	January 31, 2028

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