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Clinical Trial Summary

To measure surgical success of open vs closed conjunctiva with Xen implantation.


Clinical Trial Description

This retrospective, single-arm multicenter study included >100 eyes (>100 patients) with glaucoma refractory to medical therapy. All surgeries were performed by two groups of surgeons at Johns Hopkins University and the sub-investigator group at New York University. Group 1: Xen with open conjunctiva for positioning and application of mitomycin. The Xen was placed through the sclera either ab-interno or ab-externa. Group 2 had Xen placed ab-interno or ab-externa (trans conjunctival), but the conjunctiva was not opened for positioning or application of mitomycin-C. Success rates will be determined based on need for re-intervention and intraocular pressure control. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04406467
Study type Observational
Source Johns Hopkins University
Contact
Status Completed
Phase
Start date November 19, 2017
Completion date August 26, 2020

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