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NCT04234932 Clinical Trial

Short-term Effect of Rho-kinase Inhibitor on Retinal Circulation

Glaucoma, Open-Angle Clinical Trial

Official title:
Short-term Effect of Rho-kinase Inhibitor on Retinal Circulation

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04234932
Other study ID # 19-12-005
Secondary ID
Status Recruiting
Phase Early Phase 1
First received
Last updated
Start date January 6, 2020
Est. completion date January 2021

Study information
Verified date April 2020
Source University of the Incarnate Word
Contact Mary Jo Bilicek
Phone 210-805-3565
Email bilicek@uiwtx.edu
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Investigate changes in optical coherence tomography angiography of the optic nerve and macula following topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution.

Recruitment information / eligibility
Status Recruiting
Enrollment 10
Est. completion date January 2021
Est. primary completion date January 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Normal ocular health

Exclusion Criteria:

- Females who are or may be pregnant or who are nursing

- Uncontrolled hypertension

- Allergy to netarsudil or latanoprost

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Netarsudil Ophthalmic
Topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution (Rhopressa and Roclatan)

Locations
Country Name City State
United States University of the Incarnate Word San Antonio Texas

Sponsors (1)
Lead Sponsor Collaborator
University of the Incarnate Word

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Peripapillary capillary perfusion density Mean change in peripapillary capillary perfusion as assessed using optical coherence tomography angiography 90 minutes
Secondary Macular capillary perfusion density Mean change in macular capillary perfusion as assessed using optical coherence tomography angiography 90 minutes
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