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NCT01254058 Clinical Trial

Saccadic Eye Movements Are Impaired In Glaucoma

Glaucoma, Open-Angle Clinical Trial

Official title:
Novel Vision Testing Paradigms for Patients With Glaucoma

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT01254058
Other study ID # REB 06-056
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date July 2010
Est. completion date April 2020

Study information
Verified date September 2019
Source St. Michael's Hospital, Toronto
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to determine whether rapid eye movements called saccades are impaired in glaucoma, a neurodegenerative disease of visual pathways.

Description:

Eye movements that quickly scan a visual scene are critical to a number of daily activities including driving. It is not known whether rapid eye movement called saccades, are altered in glaucoma.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 40
Est. completion date April 2020
Est. primary completion date April 2020
Accepts healthy volunteers No
Gender All
Age group 40 Years to 80 Years
Eligibility Inclusion Criteria:

- Ages from 40-80 years. Primary open angle glaucoma is defined by characteristic glaucomatous optic nerve head findings and the presence of corresponding visual field deficits in one or both eyes. All control subjects will be age-matched, with no ocular medical or surgical history, and a completely normal eye examination. Age-matched controls will be recruited from local hospital personnel and accompanying relatives.

Exclusion criteria:

- Any patient with a history of other eye disease, neurological disease or neurodegenerative disorder, or history of incisional ocular surgery within the previous month will be excluded.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Canada St. Michael's Hospital Toronto Ontario

Sponsors (1)
Lead Sponsor Collaborator
St. Michael's Hospital, Toronto

Country where clinical trial is conducted

Canada, 

References & Publications (2)

Gupta N, Krishnadev N, Hamstra SJ, Yücel YH. Depth perception deficits in glaucoma suspects. Br J Ophthalmol. 2006 Aug;90(8):979-81. Epub 2006 May 3. — View Citation

Kanjee R, Yücel YH, Steinbach MJ, González EG, Gupta N. Delayed saccadic eye movements in glaucoma. Eye Brain. 2012 Nov 26;4:63-68. doi: 10.2147/EB.S38467. eCollection 2012. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Delay in saccades April 2014
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