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Glaucoma, Open-Angle clinical trials

View clinical trials related to Glaucoma, Open-Angle.

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NCT ID: NCT04949802 Completed - Glaucoma Clinical Trials

Glaucoma Surgery Using the ViaLase Laser System

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Prospective, single-center, multi-cohort clinical trial of ViaLase Laser for the reduction of IOP in patients with open angle glaucoma.

NCT ID: NCT04944290 Completed - Ocular Hypertension Clinical Trials

To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes

Start date: May 28, 2021
Phase: Phase 3
Study type: Interventional

To compare the efficacy and safety of Perrigo's product to an FDA approved product in the treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Both Eyes.

NCT ID: NCT04911387 Completed - Glaucoma Clinical Trials

iCare® Home vs Goldmann Applanation Tonometry

Start date: April 1, 2020
Phase:
Study type: Observational

Self-tonometry with iCare Home is regularly performed at Sankt Erik's Eye Hospital since a few years back. The purpose of this study was to show that the eye pressure measurements made with iCare® Home by patients / relatives do not vary more than those made with the standard method, Goldman applanation tonometry (GAT), by different healthcare professionals. This will hopefully confirm the usefulness of self-tonometry.

NCT ID: NCT04910100 Completed - Ocular Hypertension Clinical Trials

Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension

Start date: April 15, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety (in the eye and throughout the body) and effectiveness of nebivolol (0.5 and 1 percent) and timolol (0.5 percent) eye drop suspensions. These eye drops will be compared to timolol 0.5 percent eye drop solution in participants with open angle glaucoma (the most common type of glaucoma) or high eye pressure (ocular hypertension).

NCT ID: NCT04903366 Completed - Clinical trials for Glaucoma, Open-Angle

Absorption and Safety of Topical Timolol to Treat Chronic Wounds

Start date: November 21, 2017
Phase:
Study type: Observational

Topical timolol has been used primarily as eye drops to treat glaucoma for many years. Recent clinical experience has broadened its off-label use for a number of skin conditions, including slow-healing wounds. While there have been extensive safety studies performed on timolol administration to treat the eye, to date, no studies have documented absorption of timolol after applied on chronic wounds. Thus, the purpose of this study is to determine the blood levels of timolol in patients after topical administration to a chronic wound, and compare these levels with those of patients after administration of the same drug formulation on the eye for the indication of glaucoma.

NCT ID: NCT04890106 Completed - Clinical trials for Glaucoma, Open-Angle

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% to LUMIGAN® In The Treatment of Chronic Open-Angle Glaucoma

Glaucoma
Start date: October 2, 2021
Phase: Phase 3
Study type: Interventional

This is a randomized, double-masked, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle glaucoma or ocular hypertension in both eyes. Test Product - Bimatoprost Ophthalmic Solution, 0.01% of Mankind Pharma Limited, India Reference Product - LUMIGAN® (Bimatoprost Ophthalmic Solution) 0.01% of Allergan, Inc.,

NCT ID: NCT04888156 Completed - Glaucoma Clinical Trials

Impact of Self-tonometry on Glaucoma Treatment Decision.

Start date: May 10, 2021
Phase:
Study type: Observational

Self-tonometry with iCare Home is performed by one hundred patients annually at Sankt Erik's Eye Hospital. The investigators want to evaluate the impact that self-tonometry results have on the clinician's choice of glaucoma treatment. The investigators also want to evaluate how often pressure peaks occur outside the clinic's opening hours.

NCT ID: NCT04872348 Completed - Clinical trials for Glaucoma, Open-Angle

An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)

Start date: July 1, 2021
Phase:
Study type: Observational

The purpose of this study is to evaluate the safety and effectiveness of the OMNI® Surgical System in subjects who have undergone canaloplasty and trabeculotomy using OMNI® Surgical System without any concomitant surgery in pseudophakic eyes with mild to moderate primary open angle glaucoma (POAG) at least 150 days prior to enrollment.

NCT ID: NCT04830397 Completed - Ocular Hypertension Clinical Trials

Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).

Start date: March 31, 2021
Phase: Phase 2
Study type: Interventional

Evaluating the safety and tolerability of QLS-101 versus timolol maleate ophthalmic solution in glaucoma or ocular hypertension.

NCT ID: NCT04828057 Completed - Clinical trials for Primary Open Angle Glaucoma

Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glaucoma or Ocular Hypertension: Clinical Effectiveness, Tolerability and Safety in a Real World Setting

Start date: September 1, 2021
Phase:
Study type: Observational

The primary objective of this study is to assess the effectiveness of Tafluprost / Timolol in controlling ocular hypertension, as measured by mean change in intra-ocular pressure (IOP) from baseline to after 6 months of treatment from initiation, in patients with open angle glaucoma (OAG) or ocular hypertension (OHT), who do not respond sufficiently to initial topical treatment, in routine clinical practice.