OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients

Glaucoma Open-Angle Primary Clinical Trial

Official title:

OCTA as a New Biomarker in the Pathogenesis of Primary Open Angle Glaucoma

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05455567
• Other study ID #: 0102/22
• Status: Completed
• Start date: February 1, 2022
• Est. completion date: May 15, 2022

Study information

• Verified date: July 2022
• Source: Federico II University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of the present study was to examine and measure SFCT and CCVD using respectively EDI-OCT and OCTA in preperimetric and advanced glaucomatous eyes, in order to shed light on the vascular pathogenesis of glaucoma disease.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 57
• Est. completion date: May 15, 2022
• Est. primary completion date: April 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 40 Years to 75 Years

Eligibility

Inclusion Criteria:• age older than 40 years

• diagnosis of glaucoma

• absence of diabetes, heart diseases, hypertension

• absence of drug intake

• absence of vitreoretinal, vascular retinal diseases

• absence of previous ocular surgery and congenital eye diseases.

• absence of errors of refraction

• absence of lens opacities

• absence of low-quality OCT and OCTA images

Exclusion Criteria:

• age younger than 40 years

• presence of diabetes, heart diseases, hypertension

• vitreoretinal and vascular retinal diseases

• previous ocular surgery and congenital eye diseases

• errors of refraction

• lens opacities

• low-quality OCT and OCTA images

Related Conditions & MeSH terms

• Glaucoma
• Glaucoma Open-Angle Primary
• Glaucoma, Open-Angle

Intervention

Diagnostic Test:
• OCTA
Choriocapillary vessel density calculated with OCTA

Locations

Country	Name	City	State
Italy	University of Naples "Federico II"	Naples

Sponsors (1)

Lead Sponsor	Collaborator
Federico II University

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The measurements of choroidal thickness and choriocapillary vessel density in patients with open angle glaucoma.	correlation of measurement of choroidal thickness and choriocapillary vessel density in three different patients groups	up to 5 months