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Glaucoma, Angle-Closure clinical trials

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NCT ID: NCT06252246 Completed - Clinical trials for Primary Angle Closure Glaucoma

The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province

Start date: October 1, 2017
Phase:
Study type: Observational

BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system. Treatment guidelines of each stage is differenced. Therefore, factors that affect to treatment should be explored to plan for taking care patients in the future. OBJECTIVES: The study aimed to examine the effects of cataract surgery by phaco- emulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients.

NCT ID: NCT06184620 Completed - Clinical trials for Primary Angle Closure Glaucoma

Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

Start date: December 1, 2020
Phase:
Study type: Observational

The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

NCT ID: NCT06143943 Completed - Clinical trials for Glaucoma, Angle-Closure

Anterior Segment Anatomic Parameters for Risk Profiling of Primary Angle-closure Glaucoma

Start date: November 22, 2022
Phase:
Study type: Observational

The goal of this observational study is to examine the anterior segment anatomical parameters associated with the scleral spur and cornea for risk profiling of primary angle-closure glaucoma (PACG). The main question it aims to answer is: • Are there new anatomical parameters of the anterior segment of the eye that can be used early for risk profiling for PACG? Researchers will compare PACG and narrow angle groups to see if there are some anatomical parameters that can distinguish the two.

NCT ID: NCT06120621 Completed - Clinical trials for Narrow-Angle Glaucoma

Combined VCST With Phacoemulsification Versus Phacoemulsification in Primary Angle Closure Glaucoma

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

As ab externo metal probe trabeculotomy cannot achieve 360-degree circumferential angle surgery, prolene suture can be used to achieve this without the need for an illuminated microcatheter. In order to combine the advantages of the use of viscoelastic and those of circumferential trabeculotomy, this technique (Visco-Circumferential-Suture- Trabeculotomy "VCST") was previously used successfully in PCG. (7) In the current study , the authors hypothesize that combination of VCST with phacoemulsification in primary angle closure glaucoma patients may have an added affect to phacoemulsification alone in cases with more extent of angle damage and that the injection of a viscoelastic into both ends of the unroofed SC before its cannulation by a polypropylene suture and subsequent circumferential trabeculotomy may facilitate circumferential cannulation of SC and hence the trabeculotomy and increase the success of the technique

NCT ID: NCT06000176 Completed - Clinical trials for Glaucoma,Primary Open-Angle ,Primary Angle Closure

Comparison of Optical Coherence Tomography Angiography Microvascular Changes in Primary Open Angle and Primary Angle Closure Glaucoma

Start date: April 5, 2022
Phase:
Study type: Observational

This work aims to study the peripapillary and macular microvascular changes in primary open angle and primary angle closure glaucoma using Optical Coherence Tomography Angiography (OCTA).

NCT ID: NCT05052242 Completed - Clinical trials for Primary Angle Closure Glaucoma

Evaluation of Ocular Biometry in PACD With Two Swept Source Optical Coherence Tomography Devices

Start date: May 1, 2020
Phase:
Study type: Observational

Purpose: To investigate agreement between 2 swept source OCT biometers, IOL M.aster700 and Anterion, in various ocular biometry and intraocular lens (IOL) calculations of primary angle-closure disease (PACD). Methods: This was a prospective study conducted in a tertiary eye care centre involving biometric measurements obtained with 2 devices in phakic eye with diagnosis of PACD. Mean difference and intraclass correlation coefficient (ICC) with confidence limits were assessed, and calculations of estimated residual refraction of the IOL were analysed using Barrett's formula.

NCT ID: NCT04972435 Completed - Senile Cataract Clinical Trials

Effect of Multifocal Intraocular Lens on Contrast Sensitivity in Primary Angle-Closure Patients

Start date: January 2, 2014
Phase: N/A
Study type: Interventional

This prospective study included patients with primary angle-closure (PAC or primary angle-closure glaucoma (PACG) and visually significant cataract. Phacoemulsification with multifocal intraocular lens (MIOL) or monofocal IOL (mIOL) (patient preference) was performed. Collected data included best-corrected distant visual acuity (BCVA), intraocular pressure (IOP), anterior chamber depth (ACD), and contrast sensitivity (CS) measured at spatial frequency 1.5, 3.0, 6.0, 12.0, and 18.0 cycles per degree (CPD) preoperatively, and at 2-6 months postoperatively. Preoperative and postoperative parameters were compared to evaluate the effect of MIOL on CS in eyes with PAC or PACG.

NCT ID: NCT04683055 Completed - Glaucoma Clinical Trials

Phaco-Trabeculotomy Vs Phaco-Trabeculectomy

PDT vs PT
Start date: October 28, 2020
Phase: N/A
Study type: Interventional

A prospective, randomized comparative study on adult patients with synechial angle closure glaucoma.

NCT ID: NCT04622605 Completed - Clinical trials for Primary Angle Closure Glaucoma

Hydrus Microstent and Lens Extraction for the Treatment of Primary Angle-Closure Glaucoma

Start date: June 13, 2017
Phase: N/A
Study type: Interventional

This study is a prospective evaluation of the Hydrus Microstent for the treatment of Primary Angle Closure (PAC) and Primary Angle Closure Glaucoma (PACG) with adjunctive cataract. A total of 20 subjects will be successfully treated with one Hydrus device after completion of cataract extraction with phacoemulsification followed by IOL replacement (HMS cohort), and 10 eyes will be treated with phacoemulsification cataract extraction and IOL replacement only (PCS group). Since cataract surgery is standard of care for this condition, eligible fellow eyes from the HMS cohort may be enrolled into the PCS group. To avoid selection bias in this non-randomized study, the first 20 consecutive qualifying subjects will be treated with Hydrus and the next 10 consecutive qualifying eyes will be treated with cataract surgery only.

NCT ID: NCT04476810 Completed - Surgery Clinical Trials

Long Term Outcome of Combined Phacoemulsification and Excisional Goniotomy With the Kahook Dual Blade

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Purpose: Characterize changes in intraocular pressure (IOP), IOP-lowering medications, and visual acuity (VA) through 3 years in patients undergoing combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade (phaco-KDB), with simultaneous goniosynechialysis in cases of angle-closure glaucoma, by a single surgeon (A.H.) in King Fahd Hospital of the University, Dammam, Saudi Arabia. Methods: Prospective, non-comparative, uncontrolled, non-randomized interventional case series. Consecutive patients with medically-treated glaucoma and visually-significant cataract underwent combined surgery. Subgroup analysis of glaucoma subtypes was performed.