Clinical Trials Logo

Clinical Trial Summary

Data are currently insufficient to guide the management of very small gastrointestinal stromal tumors(GISTs)(< 2 cm) discovered incidentally on endoscopy,this study is designed to collect the medical records of patients in different treatment group with long-term follow-up data,and attempts to evaluate the usefulness of regular endoscopic ultrasound(EUS)surveillance and the necessity,safety and feasibility of endoscopic submucosal dissection(ESD)for small GISTs,thus provide evidence for the revision of the guideline.


Clinical Trial Description

OBJECTION:to evaluate the usefulness of regular endoscopic ultrasound(EUS) surveillance and the necessity,safety and feasibility of endoscopic submucosal dissection(ESD) for small GISTs(<2cm),thus providing evidences for the revision of the guideline.

OUTLINE:This is a randomized controlled trial. Eligible patients are divided into 2 group with 45 in each.The experimental group undergo ESD for GISTs,while the investigators do no treatment to the control group.Then,the 2 groups will be follow up for 5 years.All data are analysed with the Statistical Product and Service Solutions(SPSS)statistical software. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03082079
Study type Interventional
Source Nanfang Hospital of Southern Medical University
Contact yue li, Doctor
Phone 15975537291
Email liyue_1989919@126.com
Status Not yet recruiting
Phase N/A
Start date June 1, 2017
Completion date September 30, 2021

See also
  Status Clinical Trial Phase
Recruiting NCT05957367 - A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies Phase 1/Phase 2
Completed NCT01770405 - Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract N/A
Active, not recruiting NCT03556384 - Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST) Phase 2
Recruiting NCT05895942 - Exploring the Molecular Mechanism Based on KIT Mutation
Completed NCT01459757 - Non-Interventional Retrospective Correlation Of Tumor Mutational Status To Clinical Benefit Of GIST Patients Treated With Sunitinib N/A
Completed NCT00979381 - Study of the Immunoresponse in Patients Treated With a Tyrosine Kinase Inhibitor N/A
Completed NCT00399152 - Perifosine + Sunitinib Malate for Patients With Advanced Cancers Phase 1
Recruiting NCT03715933 - Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas Phase 1
Completed NCT04599660 - Study in Low Risk Gastrointestinal Stromal Tumor (GISTs)
Completed NCT05400018 - Clinical Evaluation of Genetron D842V PCR Kit in GIST Patients
Recruiting NCT03475953 - A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors Phase 1/Phase 2
Not yet recruiting NCT04825470 - Liver Transplantation for Unresectable GIST Liver Metastases N/A
Recruiting NCT00687778 - 11C-Acetate PET/CT Non-FDG-Avid Tumors N/A
Completed NCT00979329 - Study on the Influence of Sunitinib and Sorafenib on Fatigue, QoL, Depression in Patients With Metastatic RCC or GIST N/A
Active, not recruiting NCT04927260 - French Long Term Registry With Longitudinal Follow up of PDGFRA D842V-GIST Patients
Completed NCT03465722 - (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST Phase 3
Completed NCT03880617 - Distress, Medication Adherence and Care Needs in Patients With CML and GIST Receiving Oral Targeted Therapy
Recruiting NCT03896958 - The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)
Completed NCT01323400 - Efficacy of Pazopanib in Gastrointestinal Stromal Tumors (GIST) Phase 2
Recruiting NCT05804331 - The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study