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Effect of Probiotics on Oral Homeostasis During Oral Hygiene Discontinuation

Gingivitis Clinical Trial

Official title:
Effect of Probiotics on Oral Homeostasis During Oral Hygiene Discontinuation

Clinical Trial Summary

The present study is a double-blinded randomized clinical trial with a duration of 28 days.

Clinical Trial Description

The present study is a double-blinded randomized clinical trial with a duration of 28 days. 80 orally and systemically healthy participant will be allocated in the test (probiotic) and the control (placebo) group at baseline. The intervention is oral hygiene discontinuation, which will be applied at baseline and continue through day 14, followed by 14 days with regular oral care. Clinical measurements and sampling will be performed at baseline, day 14 and day 28 Primary endpoint: Changes in microbial composition. Secondary endpoints: Changes in clinical and immunological parameters ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05268757
Study type Interventional
Source University of Copenhagen
Contact
Status Completed
Phase N/A
Start date January 5, 2022
Completion date June 1, 2022
View Details
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