Gingivitis Clinical Trial
Official title:
Clinical and Biochemical Evaluation of Dental and Periodontal Conditions in Children With Juvenile Idiopathic Arthritis
Verified date | January 2022 |
Source | Marmara University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Aimed to be done in the planned thesis to evaluate the dental and periodontal health of patients with newly diagnosed JIA and healthy-periodontal problems with cytokines from saliva and oxidative stress markers non-invasively, and thus, to determine the markers' evaluability in terms of markers in determining the state of inflammation among individuals with and without the disease.
Status | Active, not recruiting |
Enrollment | 114 |
Est. completion date | September 1, 2022 |
Est. primary completion date | May 15, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 5 Years to 16 Years |
Eligibility | Inclusion Criteria: - healty patients Exclusion Criteria: - used antibiotics within the last 3 months |
Country | Name | City | State |
---|---|---|---|
Turkey | Marmara University Faculty of Dentistry | Istanbul | Maltepe |
Lead Sponsor | Collaborator |
---|---|
Marmara University |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | biochemical evaluation of saliva in juvenile idiopathic arthritis | Saliva samples were taken from the patients and the levels of interleukin-17, TNF alpha and Total antioxidant status in the saliva were measured with ELISA kits. | baseline | |
Secondary | Evaluation of oral hygiene in patients with juvenile idiopathic arthritis | The number of caries in the patient was evaluated with the DMFT-dft index. | baseline | |
Secondary | Evaluation of periodontal health in patients with juvenile idiopathic arthritis | Silness-Loe plaque index (PI) was used to assess periodontal health. | baseline | |
Secondary | Examination of periodontal health in patients with juvenile idiopathic arthritis | Gingival index (GI) was also used to examination periodontal health. | baseline | |
Secondary | periodontal health in patients with juvenile idiopathic arthritis | Bleeding on prob index were used for periodontal health examination. | baseline |
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