The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark & Centella

Status Completed

Clinical Trial Summary

This study aims to evaluate the effect of novel mouthrinse formulations containing bamboo salt, magnolia bark and centella asiatica extracts on gingivitis and dental plaque. Participants uses mouthrinses which contain bamboo salt, magnolia bark and centella asiatica extracts and the same participants will also use placebo for tooth brushing by cross-over design.

Clinical Trial Description

This is a randomized clinical intervention study with a cross-over design. The subjects are randomly allocated to one of the three experimental groups: 1) the control; 2) ASM group for aqueous single-phase mouthrinse; 3) OTM group for oil-water two-phase mouthrinse. The experimental mouthrinses all contain sodium fluoride and the ASM and OTM contain additional ingredients of bamboo salt, magnolia bark and centella asiatica extracts. For the OTM, 50% essential oil is added to create an oil-water two-phase mouthrinse. Subjects are instructed to use the prescribed mouthrinse to gargle their mouth for one minute, twice daily for two weeks. The completion of each experiment regimen is followed by a 2-week washout period, after which the subjects of each group were permutated to the next mouthrinse trial until all three groups underwent the three mouthrinse trial regimen. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03047798
Study type	Interventional
Source	Seoul National University
Contact
Status	Completed
Phase	Phase 3
Start date	June 1, 2014
Completion date	October 31, 2014

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT05568290` - Interleukin-38 Levels in Individuals With Periodontitis
Completed	`NCT04402996` - Meteorin-like Levels in Individuals With Periodontitis
Not yet recruiting	`NCT06016023` - Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker
Not yet recruiting	`NCT05497895` - The Assessment of Clinical Efficacy of Topical Application of 5% Thymoquinone Gel for Gingivitis Patients	Early Phase 1
Completed	`NCT02552589` - Effect of Toothpaste on the Reduction of Plaque and Inflammation	N/A
Completed	`NCT02884817` - Essential Oil+ELA, Plaque and Gingivitis	Phase 4
Completed	`NCT02633345` - Effects on Tablets Containing Probiotic Candidate Strains	N/A
Completed	`NCT02980497` - Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study	N/A
Completed	`NCT02515929` - Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs	Phase 4
Unknown status	`NCT01956656` - Efficacy Of Lotus Leaves In Management Of Plaque Induced Gingivitis	N/A
Completed	`NCT02235532` - Effects of Aloe Vera Toothpaste on Periodontal Parameters	N/A
Completed	`NCT01941797` - Experimental Peri-implant Mucositis in Humans	N/A
Completed	`NCT02508987` - Obesity and Oxidative Stress in Patients With Different Periodontal Status	N/A
Unknown status	`NCT01197105` - Evaluation Study of a Mouthwash Based on Schinus Terebinthifolius to Treat Gingivitis in Children	Phase 1/Phase 2
Completed	`NCT01593540` - Clinical Examination of Metal Free Interdental Brushes	Phase 4
Completed	`NCT01236963` - Essential Oils Mouth Rinse and Dental Floss: Efficacy on Interproximal Gingivitis and Dental Plaque Accumulation	N/A
Completed	`NCT02102295` - Effects of Antioxidant Dentifrice on Gingivitis	Phase 3
Completed	`NCT06140784` - A Clinical Study to Assess the Gingivitis and Plaque Effects of Various Dentifrices	N/A
Completed	`NCT02937636` - To Investigate the Gingivitis Efficacy of a Stannous Fluoride Dentifrice in a Chinese Population	N/A
Completed	`NCT06212908` - Assessment of Periodontal Therapy and Biofilm Management in Breast Cancer	N/A

The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark and Centella Asiatica on Reducing Plaque and Gingivitis

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms