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Gingivitis clinical trials

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NCT ID: NCT03471325 Completed - Gingivitis Clinical Trials

A Comparison of the Outcomes of Two Existing Routine Clinical Therapies for Dental Prophylaxis

Start date: December 8, 2016
Phase: N/A
Study type: Interventional

Background: In most practices, conventional in-office prophylaxis starts immediately with scaling and polishing. Therefore, this project was designed to challenge tradition by comparing plaque removal efficacy of rubber cup and air polishing in two scenarios, one where plaque was disclosed prior to treatment and the other where plaque was not disclosed. Methods: In this randomized, single blind, split-mouth design clinical trial, healthy, non-smoking participants with poor oral hygiene were recruited. Quadrants in each participant were randomly assigned to 4 treatment groups, which were plaque disclosure with rubber cup polishing, no plaque disclosure with rubber cup polishing, plaque disclosure with air polishing, and no plaque disclosure with air polishing. Examiners were calibrated and masked to the treatment rendered in each quadrant. Post treatment satisfaction questionnaires for both participants and operators were completed. Plaque scores for each quadrant and treatment time were the recorded outcome measures.

NCT ID: NCT03455192 Completed - Smoking Clinical Trials

Synbiotic as an Adjunct to Mechanical Treatment of Gingivitis

Start date: July 22, 2014
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of oral administration of synbiotic tablets on the clinical parameters and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF) in smokers and non-smokers with gingivitis. This study designed as a double-blind randomized placebo-controlled clinical trial.

NCT ID: NCT03445286 Completed - Gingivitis Clinical Trials

Silver Diamine Fluoride and Gingivitis in Geriatric Patients

Start date: January 29, 2019
Phase: N/A
Study type: Interventional

Gingivitis in the geriatric population is one of the growing global public health concerns, thus finding the most effective and non-invasive approach to prevent and treat gingivitis in the geriatric population is essential to prevent tooth loss and maintain oral health and function. Silver Diamine Fluoride (SDF) is Class II medical device. It was cleared for use in US August 2014 and became commercially available in April 2015. It is a chemical agent which has bifunctional properties. The silver itself kills caries causing bacteria directly. Silver and fluoride together interact to form fluorapatite, in addition, assist in hardening the teeth and preventing further demineralization. Even though SDF has been approved in dental caries prevention and treatment, there are no published studies or evidence that evaluated the direct effect of SDF on gingivitis. If SDF improves or prevents gingivitis is unknown. The main goal of this clinical study is to investigate the effect of SDF on gingival status in geriatric patients with gingivitis. There is an urgent need to solve this common oral disease in the geriatric population. The logic for this research in a geriatric population is to find the most effective approach to treat gingivitis to prevent tooth loss and maintain oral health and function. To find an effective approach to treat gingivitis in the geriatric group, we will investigate the effectiveness of SDF application on gingival tissues in this group. The patients with gingivitis will be randomly allocated to two groups: group1(case group) will receive SDF application and group 2 (control group) will receive a normal saline application. The gingiva will be evaluated for both groups at baseline before the application. Then 2 weeks and 4 weeks after the last application of the intervention. In addition, a sample of plaque will be taken from the teeth selected in this study by swab using the dental kit (Ubiome) before and after both applications to quantify the presence of bacterial pathogen at baseline and follow up visits. The feasibility of this proposed therapy is supported by published literature that has shown that SDF was effective in dental and root caries prevention and treatment in geriatric patients.

NCT ID: NCT03439969 Completed - Gingivitis Clinical Trials

A 8-month Study on the Use of Intra-oral Camera and Text Messages on Gingivitis Control

Start date: June 1, 2014
Phase: N/A
Study type: Interventional

To investigate the effects of using an intra-oral camera (IOC) during supportive periodontal therapy, and oral hygiene mobile text messages (SMS) between appointments on clinical, behavioral and psychological parameters of patients with gingivitis.

NCT ID: NCT03421145 Completed - Plaque Clinical Trials

A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis

Start date: December 17, 2017
Phase:
Study type: Interventional

Rinse contains an anti-plaque agent that helps prevent the accumulation of dental plaque associated with gingivitis.

NCT ID: NCT03418246 Completed - Gingivitis Clinical Trials

Cervical Carious Lesions Restored With Calcium Silicate Based Cement (Biodentine) Compared With Glass-ionomer Cement

Start date: January 3, 2015
Phase: N/A
Study type: Interventional

This study will test if applying calcium silicate cements (Biodentine) to restore cervical carious lesions might adversely affect the gingival health in comparison with conventionally used tooth colored material (GIC)

NCT ID: NCT03416985 Completed - Dental Plaque Clinical Trials

A Comparative Study of Electric Toothbrushes for the Efficacy Plaque Removal and the Effect on Plaque Accumulation and Gingivitis.

Start date: January 2, 2018
Phase: N/A
Study type: Interventional

It is well accepted that the greatest contributor to the health of the periodontium and dentition is regular and thorough dental plaque removal, typically by means of adequate toothbrushing. Although patients are typically informed about the risks of substandard oral hygiene and the contributing factors in oral/dental disease by dental professionals, research has shown that an undesirably high proportion of adults find thorough toothbrushing with a standard manual toothbrush to achieve a plaque-free state challenging, as evidenced by high worldwide levels of gingivitis and/or periodontitis.

NCT ID: NCT03390452 Completed - Oral Hygiene Clinical Trials

Mobile Phone Messaging To Improve Oral Hygiene Among Primary School Children in Pakistan

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Oral health is an important component of general health and oral cavity acts as a mirror to the health of individuals and communities. Inadequate focus on primary prevention of oral diseases, poses a sizeable challenge for numerous countries, especially low and middle income countries. Mobile phone technology is relatively new and its successes in chronic disease is well documented but there is little evidence available in its use for improving oral health and dietary habits of children. This will be a Pilot Randomized Control Trial (RCT) . It will be conducted in public and private sector schools of Quetta city, Pakistan. Study will comprise of intervention and a control arm. Duration of intervention is 6 months. In the intervention group, study participants will be the parents. School teachers will send oral health education and reminder messages on frequent intervals to educate children's parents on oral hygiene and reinforce their behaviors to improve their child oral health. The primary school children in the control group will not receive any intervention

NCT ID: NCT03381339 Completed - Gingivitis Clinical Trials

Powertoothbrushing for Treating Gingivitis

Start date: December 5, 2017
Phase: N/A
Study type: Interventional

In this three-month interventional clinical trial for the treatment of gingivitis the investigators will assess the use of an oscillating-rotating powered toothbrush in comparison to the use of a manual toothbrush over 12-weeks in the absence of interproximal hygiene.

NCT ID: NCT03378401 Completed - Clinical trials for Inhibition of Plaque Formation (by Gingivitis-Index =1.5)

Study to Assess the Inhibition of Plaque Formation in Subjects With a Gingival Index ≤1.5

Start date: January 11, 2018
Phase: Phase 3
Study type: Interventional

The objective of the study is to demonstrate the superiority of 0.1% octenidine mouthwash (Octenidin Mundspüllösung, OML) to placebo (PLAC) in the inhibition of plaque formation. The study will consist of a 14-day screening period and a 5-day treatment period.