Applanation Tonometry in the Diagnosis of Giant Cell Arteritis — TAAT  

Giant Cell Arteritis Clinical Trial

Official title: Applanation Tonometry in the Diagnosis and Monitoring of New-Onset Giant Cell Arteritis

Status Not yet recruiting

Clinical Trial Summary

The objective of this observational prospective cohort study is to assess if:

1. temporal artery stiffness measurement by applanation tonometry may help predict a final diagnosis of new-onset GCA

2. In patients with a diagnosis of GCA, identify if temporal artery stiffness measured by applanation tonometry improves with treatment.

Clinical Trial Description

Applanation tonometry (a technique that measures the pulsation of the arteries with a probe, like ultrasound), measures the stiffness of the arteries. This technique is increasingly used for the diagnosis and monitoring of high blood pressure in routine practice. The presence of systemic inflammation, was already demonstrated to cause increased arterial stiffness, at various arterial levels, in rheumatic diseases such as rheumatoid arthritis or Takayasu's arteritis.

Objectives :

1. To establish if temporal artery stiffness measurement may help predict a final diagnosis of new-onset GCA

2. In patients with a diagnosis of GCA, identify if temporal artery stiffness improves with treatment ;

Related Conditions & MeSH terms

• Arteritis
• Giant Cell Arteritis
• Polymyalgia Rheumatica

• NCT number: NCT05703763
• Study type: Observational
• Source: Hopital du Sacre-Coeur de Montreal
• Contact: Jean-Paul Makhzoum, MD
• Phone: 514-338-2222
• Email: jean-paul.makhzoum@umontreal.ca
• Status: Not yet recruiting
• Start date: March 2024
• Completion date: August 2027