Abatacept for the Treatment of Giant Cell Arteritis

Status Active, not recruiting

Clinical Trial Summary

This randomized, double-blind, placebo-controlled trial will seek to determine the efficacy of abatacept in GCA. To examine this objective, 62 eligible patients who have newly diagnosed or relapsing GCA within 8 weeks prior to screening will be randomized at a 1:1 ratio to receive subcutaneous abatacept 125mg/week or placebo. Patients who achieve remission will remain on their blinded assignment for 12 months at which time abatacept/placebo will be stopped. Patients who do not achieve remission by Month 3, who experience a relapse within the first 12 months will have the option of receiving open-label abatacept for a maximum of 12 months.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04474847
Study type	Interventional
Source	University of Pennsylvania
Contact
Status	Active, not recruiting
Phase	Phase 3
Start date	March 15, 2021
Completion date	December 2026

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See also
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