Gestational Age Clinical Trial
Official title:
Urine and Serum Concentrations of Pregnancy-Associated Compounds During Gestation
Investigators will collect serum and urine specimens from pregnant patients along the full pregnancy continuum, assay each specimen for selected placental proteins, and examine the relationships between concentrations of the proteins and gestational age as determined by ultrasound.
Investigators will collect serum and urine specimens from pregnant patients along with ultrasound results and information about factors that may affect the concentrations of proteins or the estimation of gestational age. Investigators will obtain data across the full pregnancy continuum but we will over sample patients within five gestational weeks before and after the 10 week mark. Investigators will assay each specimen for selected placental proteins (Human placental lactogen (HPL), Schwangerschaftsprotein 1 (SP1), Pregnancy-associated plasma protein A (PAPP-A), A Disintegrin and Metalloproteinase 12 (ADAM12), and Human chorionic gonadotropin (HGC)) and any other proteins of interest identified prior to running assays and will examine the relationships between concentrations of the proteins and gestational age as determined by ultrasound. The goal is to identify at least one compound and a concentration threshold for that compound that can be used for differentiating pregnancies of less than 10 weeks in duration from later pregnancies. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01132924 -
A Follow-up of the Early Pregnancy Study Cohort.
|
||
| Not yet recruiting |
NCT01816737 -
Fetal Blood Flow Response to Partial Occlusion by External Compression
|
N/A | |
| Completed |
NCT05433519 -
Diagnostic Accuracy of a Novel Machine Learning Algorithm to Estimate Gestational Age
|
||
| Completed |
NCT02346214 -
Smartphone Ophthalmoscope of Lens Vascularity to Estimate Gestational Age
|
N/A | |
| Completed |
NCT01140256 -
Longitudinal Zinc Intakes and Exchangeable Zinc Pool Sizes in Breastfed Small for Gestational Age vs Appropriate for Gestational Age Infants in Pakistan
|
N/A | |
| Completed |
NCT00813657 -
Resistance Exercise Training During Pregnancy: a Randomized Controlled Trial
|
Phase 4 | |
| Completed |
NCT02553577 -
Impact of Electronic Cigarettes on Perinatal Immune Responsiveness and Birth Outcomes
|