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Clinical Trial Summary

This study will be conducted to evaluate the antibacterial effect of probiotic bacteria in yogurt in decreasing streptococcus mutans count in saliva and plaque, decreasing bacterial adherence and increasing salivary pH compared to xylitol-containing chewing gum after three months.


Clinical Trial Description

The subjects will be assigned randomly into two equal groups to receive either probiotic yogurt or xylitol-containing chewing gum for three months. The probiotic yogurt is (Activia; Danone, Egypt) containing Bifidobacterium (7x107 CFU/g). The subjects assigned to probiotic yogurt group will be instructed to eat 100 g of the provided yogurt 10 minutes after dinner and not to brush their teeth until one hour later. The subjects assigned to the xylitol-chewing gum group will be instructed to chew the provided gum three times daily for five minutes after each meal. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03889015
Study type Interventional
Source Cairo University
Contact Hadier Gad, masters degree
Phone (+202) 01067838532
Email hadier.mahmoud@gmail.com
Status Not yet recruiting
Phase N/A
Start date June 2020
Completion date December 2020

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