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COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic Atrophy — COCO-GA  

Geographic Atrophy Clinical Trial

Official title:
COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic Atrophy (COCO-GA) Protocol

Clinical Trial Summary

The goal of this clinical trial is to compare measurements of geographic atrophy (GA) area between several types of imaging, in order to assess accuracy. The main question to answer is which imaging device provides measurements that are most similar to the standard of care device. Participants will be patients of a retina doctor at University Station Eye Clinic with geographic atrophy, and can expect to be in the study for 60-75 minutes.

Clinical Trial Description

This study is a single site pilot comparative imaging study in which enrolled participants will undergo dilated fundus exam as per standard of care. Study images will be obtained using Optos ultrawide field fundus autofluorescence (FAF) and both blue and green ultrawide field FAF with Zeiss Clarus. Autofluorescence (AF) imaging will also be performed on the Spectralis as it is currently the gold standard. The goal will be to obtain all images in 60-75 minutes over one visit. Images will be assessed, and area of geographic atrophy measured independently by two experienced readers. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05961332
Study type Interventional
Source University of Wisconsin, Madison
Contact Angie Adler
Phone 608-265-7557
Email amadler1@wisc.edu
Status Recruiting
Phase N/A
Start date October 6, 2023
Completion date September 2024
View Details
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