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Genotoxicity clinical trials

View clinical trials related to Genotoxicity.

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NCT ID: NCT06323603 Recruiting - Clinical trials for Occupational Exposure

Biomonitoring of Occupationally Populations Exposed to Micro and Nanoplastic

Start date: June 30, 2023
Phase:
Study type: Observational

The biomonitoring study aims to evaluate genotoxic damage and other parameters of exposure in different occupational exposed populations that work directly with different plastics.

NCT ID: NCT06021262 Recruiting - Neurotoxicity Clinical Trials

Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity

Start date: August 2023
Phase:
Study type: Observational

The aim of this observational study is to answer the following questions in individuals with acute and chronic exposure to organophosphates. The main questions to be addressed are 1. What are the prognostic values of neuroinflammatory markers? 2. What are the genotoxic effects of organophosphates? 3. what are the changes occurring in the levels of traditional oxidative stress and inflammatory markers?

NCT ID: NCT05679544 Recruiting - Clinical trials for Metabolic Disturbance

Biological Signatures Resulting From Occupational Exposure to Complex Mixtures of PAHs

PAH-ProMetGen
Start date: April 25, 2023
Phase: N/A
Study type: Interventional

This research project aims at better understanding the early biological effects resulting from occupational exposure to complex Polycyclic Aromatic Hydrocarbon (PAH) mixtures. Current biomarkers used as part of biomonitoring campaigns are biomarkers of exposure, not numerous and poorly related to health effects. The aim of this study is thus to improve our understanding of biological consequences of such exposures, both in terms of proteins deregulation, metabolism deregulation and genotoxicity.