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Genital Warts clinical trials

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NCT ID: NCT00851643 Completed - Cervical Cancer Clinical Trials

Broad Spectrum HPV Vaccine Dose Escalation Study (V502-002)

Start date: April 2006
Phase: Phase 1
Study type: Interventional

This study will examine the safety and tolerability of octavalent Human Papillomavirus (HPV) L1 Virus-Like Particle (VLP) vaccine formulated with amorphous aluminum hydroxysulfate (AAHS) and ISCOMATRIX™ (IMX). Reviews of safety and tolerability will be used to select the dose(s) of IMX for further studies of the octavalent HPV L1 VLP vaccine.

NCT ID: NCT00847340 Completed - Genital Warts Clinical Trials

Human Papillomavirus (HPV) Genotypes in Genital Warts in Colombian Population

GWprofamilia
Start date: December 2009
Phase: N/A
Study type: Observational

HPV infection has been recognized as the most prevalent sexual transmitted infection worldwide. Burden of many HPV related diseases is well known particularly regarding the different associated cancers (cervical, anal, vaginal, vulvar, oro-pharyngeal) (3) ; however, there is much less available information on the general burden of genital warts, the associated HPV types, the costs of related medical treatments and the knowledge and perceptions towards the disease and its prevention. Objectives: 1. To determine the HPV genotypes distribution in genital warts in the study population. 2. To assess the knowledge about transmission & prevention of HPV infection related diseases 3. To determine the direct medical costs of genital warts attention.

NCT ID: NCT00735462 Completed - Genital Warts Clinical Trials

Phase 3 Study of Imiquimod Creams in the Treatment of External Genital Warts

Start date: August 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether imiquimod creams are effective in treating external genital warts (EGW). The secondary objective of this study is to provide information on recurrence of EGW. Additionally the study will also look at any adverse events associated with the use of the creams. External genital and perianal warts are caused by the infection of human papillomavirus or HPV. HPV infection is a sexually transmitted disease (STD). External genital warts look like small flesh-colored, pink, or red growths on or around the external skin of sex organs or perianal area. The warts may look similar to the small parts of a cauliflower or they may be very tiny and difficult to see. They often appear in clusters of three or four, and may grow and spread rapidly. They usually are not painful, although they may cause mild pain, bleeding, and itching.

NCT ID: NCT00674739 Completed - Genital Warts Clinical Trials

Safety and Effectiveness Study of Imiquimod Creams in the Treatment of External Genital Warts

Start date: May 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether imiquimod creams are effective in treating external genital warts (EGW). The secondary objective of this study is to provide information on recurrence of EGW. Additionally the study will also look at any adverse events associated with the use of the creams. External genital and perianal warts are caused by the infection of human papillomavirus or HPV. HPV infection is a sexually transmitted disease (STD). External genital warts look like small flesh-colored, pink, or red growths on or around the external skin of sex organs or perianal area. The warts may look similar to the small parts of a cauliflower or they may be very tiny and difficult to see. They often appear in clusters of three or four, and may grow and spread rapidly. They usually are not painful, although they may cause mild pain, bleeding, and itching.

NCT ID: NCT00551187 Completed - Cervical Cancer Clinical Trials

A Study to Evaluate Tolerability and Immunogenicity of V504 Administered Concomitantly With GARDASIL (V504-001)(COMPLETED)

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate vaccine immunogenicity and how well the body tolerates V504 when given with Gardasil.

NCT ID: NCT00543543 Completed - Cervical Cancer Clinical Trials

Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001)

Start date: September 24, 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety, efficacy, and immunogenicity of V503 in comparison to GARDASIL. The primary hypotheses tested in the study were 1) V503 administered to 16- to 26-year-old adolescents and young women is generally well-tolerated, 2) V503 reduces combined incidence of Human Papillomavirus (HPV) Type 31/33/45/52/58-related disease compared with GARDASIL, and 3) V503 induces non-inferior geometric mean titers for HPV Type 6/11/16/18 antibodies compared with GARDASIL.

NCT ID: NCT00520598 Completed - Cervical Cancer Clinical Trials

Broad Spectrum HPV (Human Papillomavirus) Vaccine in 16 to 26 Year Old Women (V505-001)

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and immunogenicity of V505 in comparison to GARDASIL (TM)

NCT ID: NCT00517309 Completed - Cervical Cancer Clinical Trials

Study to Test the Safety of HPV Vaccine in Women (V501-011)(COMPLETED)

FUTURE
Start date: December 28, 2001
Phase: Phase 3
Study type: Interventional

The primary purpose of the study is to test the safety of HPV Vaccine in Women

NCT ID: NCT00501137 Completed - Cervical Cancer Clinical Trials

A Controlled Trial to Assess the Immunogenicity of a Proposed Paediatric Dosing Schedule of Human Papillomavirus Vaccine

BCGov-01
Start date: July 2007
Phase: Phase 3
Study type: Interventional

Primary objective is to determine if antibody responses to HPV types 16 & 18 are non-inferior after a 2-dose paediatric regimen as compared to a 3-dose adult regimen of Q-HPV vaccination, with responses measured at Month 7.

NCT ID: NCT00499967 Completed - Genital Warts Clinical Trials

Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts

Start date: August 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, tolerability and activity of GS-9191 ointment in the treatment of genital warts. GS-9191 ointment is intended for topical application directly to genital warts on the skin.