Genital Herpes Clinical Trial
Official title:
The VIBLOK SAfety and perFormancE Trial
Genital herpes has a high prevalence in industrialized as well as developing countries.
Genital herpes causes genital ulcers, increases risk for acquiring HIV infection, and may be
transmitted mother to child during birth with possible serious consequences.
Medical treatments and condoms only partially reduce the risk for transmission from/ to
sexual partners. Genital herpes transmission despite use of condoms is thought to be due to
transfer via skin-to-skin contact in unprotected areas, and HSV-2 transmission may be
enhanced by current shaving habits in the genital area leading to micro lesions (lacerations)
of the skin.
VIBLOK™ is a cream designed to impede the passage of viruses, such as HSV-2, across the skin.
Bench and animal experiments indicate that it can block virus transmission such as HSV-2 over
80%.
The objective of the SAFE trial is to assess the safety and performance of VIBLOK in adults
with HSV-2 infection by comparing virus detection in the extra-genital area before and after
application of the barrier cream.
n/a
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