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Pre-implantation Genetic Testing for Monogenic Disease: Single Center Experience

Genetic Disease Clinical Trial

Official title:
Pre-implantation Genetic Testing for Monogenic Disease: Single Center Experience

Clinical Trial Summary

This monocentric retrospective observational study aims to evaluate the efficacy of pre-implantation genetic testing for monogenic diseases (PGT-M). The effectiveness will be assessed in terms of live birth rate (LBR), cumulative live birth rate (CLBR) per couple, and abortion rate (AR). Considering how many cycles the participants have undergone to achieve a viable blastocyst. The secondary objective is to evaluate the incidence of aneuploidy in unaffected embryos, in order to understand the need for pre-implantation genetic testing for aneuploidy (PGT-A)in addition to PGT-M.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05936749
Study type Observational
Source Istituto Clinico Humanitas
Contact
Status Completed
Phase
Start date January 2, 2016
Completion date December 12, 2022
View Details
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