Clinical Trials Logo
  1. Home
  2. General Anesthesia
  3. NCT05275309
  4. Details
NCT05275309 Clinical Trial

Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions

General Anesthesia Clinical Trial

Official title:
Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05275309
Other study ID # H2111-072-1272
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date March 14, 2022
Est. completion date December 30, 2022

Study information
Verified date November 2021
Source Seoul National University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference between the supine and prone positions.

Recruitment information / eligibility
Status Completed
Enrollment 33
Est. completion date December 30, 2022
Est. primary completion date December 30, 2022
Accepts healthy volunteers No
Gender All
Age group N/A to 1 Year
Eligibility Inclusion Criteria: - Children <= years of age who are scheduled for surgery in the prone position under general anesthesia Exclusion Criteria: - Respiratory distress, bronchopulmonary dysplasia - Pneumothorax - Increased intracranial pressure - History of airway surgery - Cervical or thoracic surgery - Pulmonary hypertension

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Exploration of optimal PEEP in supine and prone position
General anesthesia is done in routine manner A sensor for electrical impedance tomography (EIT) is applied around the patient's chest. In supine position, lung recruitment maneuver is done, followed by decremental PEEP trial. Based on EIT parameter, optimal PEEP which induces minimal overdistension and collapse of lungs is determined. One hour after prone position, optimal PEEP is determined again.

Locations
Country Name City State
Korea, Republic of Hee-Soo Kim Seoul

Sponsors (1)
Lead Sponsor Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary Optimal PEEP level at spine position Optimal PEEP level (cmH2O) determination using electrical impedance tomography at supine position 10 minutes after intubation (supine)
Primary Optimal PEEP level at prone position Optimal PEEP level (cmH2O) determination using electrical impedance tomography at prone position 1 hour after prone positioning (prone)
Secondary Dynamic compliance measured using Electrical impedance tomography ventilation/pressure (ml/cmH2O) until 1 hour after prone positioning
Secondary regional ventilation delay measured using Electrical impedance tomography ventilation time delay during one breath (no unit) until 1 hour after prone positioning
Secondary pulmonary opening pressure measured using Electrical impedance tomography alveoli opening pressure (cmH2O) until 1 hour after prone positioning
Secondary atelectasis/overdistension ratio measured using Electrical impedance tomography The degree comparing atelectasis and overdistension (no unit) until 1 hour after prone positioning
See also
  Status Clinical Trial Phase
Completed NCT04577430 - Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period N/A
Completed NCT03708692 - Menstrual Cycle Phases on Recovery and Cognitive Function
Recruiting NCT03422315 - Population Pharmacokinetics and Clinical Individual Dosage Regimen of Propofoll Injection N/A
Completed NCT02771067 - The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position N/A
Completed NCT05063461 - Evaluation of the Analgesia Nociception Index With Varying Remifentanil Concentrations Under Sevoflurane N/A
Completed NCT03294226 - Comparison of AuraGain With I-gel for Pediatric Patients N/A
Not yet recruiting NCT03643029 - The Accuracy of the Performance and Placement Test for Predicting Supraglottic Airway Device (SAD) Position in the Hypopharynx as Confirmed With Video Laryngoscopy N/A
Completed NCT01945411 - Assessment of Facial Measurements, the Length of Mouth Corner-mandible Angle and Incisors-mandible Angle, for Determining the Proper Sizes of Oropharyngeal Airway N/A
Not yet recruiting NCT01678066 - A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor N/A
Completed NCT01705743 - Minimum Alveolar Concentration of Sevoflurane With Nitrous Oxide Inducing Isoelectric EEG Phase 4
Completed NCT00972491 - The Optimal Time to Put Laryngeal Mask Airway in the Mouth Under General Anesthesia N/A
Completed NCT01096212 - Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia Phase 4
Completed NCT00741507 - Unhealthy Alcohol Drinking and Anesthetic Requirement in Women N/A
Completed NCT00532402 - Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas N/A
Completed NCT00599066 - Intraoperative M-Entropy Measurements N/A
Completed NCT00468494 - Can Blood Glucose Levels During the Perioperative Period Identify a Population at Risk for Hyperglycemia? N/A
Recruiting NCT00492453 - Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy N/A
Recruiting NCT03745079 - Correlation Between Core Temperature and Skin Temperature Measured by 3M SpotOn
Completed NCT04094376 - Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia N/A
Enrolling by invitation NCT03672734 - Volume and pH of Gastric Contents in Patients Undergoing Gynecologic Laparoscopic Surgery During Emergence From General Anesthesia