Clinical Trials Logo
  1. Home
  2. General Anesthesia
  3. NCT03098875
  4. Details
NCT03098875 Clinical Trial

Heart Rate Variability Under Propofol and Sevoflurane

General Anesthesia Clinical Trial

Official title:
Spectral Analysis of Heart Rate Variability at BIS 25 and BIS 55 Under Propofol or Sevoflurane

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03098875
Other study ID # HRV Propofol Sevoflurane
Secondary ID
Status Completed
Phase N/A
First received January 9, 2017
Last updated March 28, 2017
Start date January 2009
Est. completion date September 2010

Study information
Verified date March 2017
Source Hôpital Armand Trousseau
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Patients were randomized into 2 groups according to the anesthetic, propofol or sevoflurane. Induction and maintenance were standardized, and after the end of surgery, two steady-state recordings were performed at BIS 25 and BIS 55. Bispectral Index and ECG were continuously recorded and cardiac autonomic nervous activity was investigated using spectral analysis of RR Interval variability

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date September 2010
Est. primary completion date December 2009
Accepts healthy volunteers No
Gender All
Age group 13 Years to 40 Years
Eligibility Inclusion Criteria:

- ASA risk classification 1 or 2,

- scheduled for middle ear surgery, or cardiovascular ANS activity.

Exclusion Criteria:

- preoperative medications that interfere with the autonomic nervous system

- preoperative medications that interfere with the central nervous system

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Sevoflurane
General anesthesia using sevoflurane as a hypnotic agent
• Propofol
General anesthesia using propofol as a hypnotic agent
• Remifentanil
General anesthesia using remifentanil as an analgesic.

Locations
Country Name City State
France Departement d'anesthesie Hopital Armand Trousseau Paris

Sponsors (1)
Lead Sponsor Collaborator
Hôpital Armand Trousseau

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Spectral analysis of heart rate variability with a bispectral index of 25 Fast Fourier Transform applied to heart rate signal recording During surgical procedure
Primary Spectral analysis of heart rate variability with a bispectral index of 55 Fast Fourier Transform applied to heart rate signal recording During surgical procedure
See also
  Status Clinical Trial Phase
Completed NCT04577430 - Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period N/A
Completed NCT03708692 - Menstrual Cycle Phases on Recovery and Cognitive Function
Recruiting NCT03422315 - Population Pharmacokinetics and Clinical Individual Dosage Regimen of Propofoll Injection N/A
Completed NCT02771067 - The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position N/A
Completed NCT05063461 - Evaluation of the Analgesia Nociception Index With Varying Remifentanil Concentrations Under Sevoflurane N/A
Completed NCT03294226 - Comparison of AuraGain With I-gel for Pediatric Patients N/A
Not yet recruiting NCT03643029 - The Accuracy of the Performance and Placement Test for Predicting Supraglottic Airway Device (SAD) Position in the Hypopharynx as Confirmed With Video Laryngoscopy N/A
Completed NCT01945411 - Assessment of Facial Measurements, the Length of Mouth Corner-mandible Angle and Incisors-mandible Angle, for Determining the Proper Sizes of Oropharyngeal Airway N/A
Not yet recruiting NCT01678066 - A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor N/A
Completed NCT01705743 - Minimum Alveolar Concentration of Sevoflurane With Nitrous Oxide Inducing Isoelectric EEG Phase 4
Completed NCT00972491 - The Optimal Time to Put Laryngeal Mask Airway in the Mouth Under General Anesthesia N/A
Completed NCT01096212 - Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia Phase 4
Completed NCT00741507 - Unhealthy Alcohol Drinking and Anesthetic Requirement in Women N/A
Completed NCT00532402 - Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas N/A
Completed NCT00599066 - Intraoperative M-Entropy Measurements N/A
Completed NCT00468494 - Can Blood Glucose Levels During the Perioperative Period Identify a Population at Risk for Hyperglycemia? N/A
Recruiting NCT00492453 - Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy N/A
Recruiting NCT03745079 - Correlation Between Core Temperature and Skin Temperature Measured by 3M SpotOn
Completed NCT04094376 - Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia N/A
Enrolling by invitation NCT03672734 - Volume and pH of Gastric Contents in Patients Undergoing Gynecologic Laparoscopic Surgery During Emergence From General Anesthesia