Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia

General Anesthesia Clinical Trial

Official title:

Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02822417
• Other study ID #: 2016 MZ/CSU/PS
• Status: Completed
• Start date: June 1, 2016
• Est. completion date: December 31, 2017

Study information

• Verified date: July 2018
• Source: Central South University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.

Description:

Recovery time of postoperative anesthesia is an important index to reflect patient's postoperative health status. The investigators want to collect patients' clinical dates and their blood samples, then extract DNA from blood samples, acquire every patients' genetic variation information. Finally, acquiring the mathematical model of the influence of clinical factors and genetic factors on the recovery time after operation, predicting the recovery time of anesthesia.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1453
• Est. completion date: December 31, 2017
• Est. primary completion date: October 10, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

1. Aged more than 18 years;

2. General anesthesia for all patients;

3. Patients underwent surgery for laparoscopic surgery, orthopedics surgery or open surgery;

4. Patients were not delivered allogeneic blood in three months;

5. Having the ability to understand and sign the informed consent.

Exclusion Criteria:

1. Pregnant or lactating women;

2. Having an immune deficiency, as a patient with HIV infection;

3. Patients with infectious diseases, such as syphilis;

4. Patients delivered allogeneic blood in three months;

5. Researchers believe that may increasing the risk of subjects or interfering clinical trial;

6. Don't have the ability to understand or sign the informed consent.

Related Conditions & MeSH terms

• General Anesthesia

Locations

Country	Name	City	State
China	Xiangya Hospital Central South University	Changsha	Hunan

Sponsors (1)

Lead Sponsor	Collaborator
Yijing He

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Recover time of anesthesia		within 24 hours