General Anesthesia Clinical Trial
Official title:
Impact of General Anesthesia on Enterocyte Damage
During non urgent surgery, general anesthesia might induce enterocyte damage. I-FABP is a performant biomarker of enterocyte damage. We aimed to study whether patient ongoing general anesthesia for non-urgent surgery have an elevation of plasma I-FABP concentration.
Inclusion criteria
- Indication of non-urgent surgery
- General anesthesia protocol using propofol and remifentanyl
- One half of the patients have a history of ischemic arteriopathy
- One half of the patients have no history of ischemic arteriopathy
Exclusion criteria
- Age < 18 years old
- Pregnant
Primary objective
Is there a significant elevation of I-FABP between the pre-anesthesic period and 11 minutes
after induction of general anesthesia ?
Secondary objectives
1. Is I-FABP elevation higher among patients with history of patent arteriopathy ?
2. Is I-FABP elevation higher among patients presenting with hypotension during anesthesia
?
;
Observational Model: Case-Only, Time Perspective: Prospective
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