General Anesthesia Clinical Trial
Official title:
Intravenous Opioid-sparing Effect of Thoracic Epidural Administration of Chirocaine (5 mg/ml) During Thoracotomy
The association of general anesthesia and of thoracic epidural anesthesia is used in
thoracic surgery with a demonstrated benefit on the risk of postoperative respiratory
complications.
The objective of the study is to analyze the influence of thoracic epidural administration
of chirocaine (5 mg/ml) on the administration of anesthetic agents (propofol and
remifentanil), these drugs being administrated using a closed-loop system with the
Bispectral Index as the controller.
Two groups of patients are compared:
- one group will receive general anesthesia and thoracic epidural administration of
saline. Chirocaine will be administered before patient's awakening,
- one group will receive general anesthesia and thoracic epidural administration of
chirocaine (5 mg/ml).
In both groups, the closed-loop system ensures that le depth of anesthesia is similar in
both groups.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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