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Gene Mutations clinical trials

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NCT ID: NCT03451877 Completed - High Myopia Clinical Trials

TGFB1 And LAMA1 Gene Polymorphisms in High Myopia

Start date: December 1, 2012
Phase: N/A
Study type: Interventional

The investigators aimed to investigate TGFB1 and LAMA1 gene polymorphisms in children with high myopia in order to determine the genetic basis of large myopic shifts causing severe visual impairment and complications. Seventy-four children with high myopia (≥6 diopters [D]; study group) and 77 emmetropic children (±0.5D; control group) were included. Genetic and polymorphism analyses were performed in the Medical Genetics Laboratory using DNA purified from the patients' blood samples.