Asthma Clinical Trial
Official title:
B2adrenergic Receptor Gene Polymorphism in Bronchial Asthma: Relation to Disease Severity and Control
The b2-adrenoceptor (b2AR) mediates the physiological responses in the airway, which include
bronchodilation, bronchoprotection. The b2-adrenoceptor (b2AR) mediates the physiological
responses in the airway, which include bronchodilation, bronchoprotection, Enhanced
mucociliary clearance.
The b2AR gene is located on chromosome 5q31-q32, a region that is genetically linked to
asthma and related phenotypes. There are three best known polymorphisms in the coding region
of the b2AR gene that can modulate the function of the receptor.
Asthma is a complex disease and has a strong genetic component in its pathogenesis. So far,
considerable efforts have been made to evaluate the association between genetic variants and
asthma risk, and numerous genes have been identified as asthma Reporting Items susceptible
genes.
The b2-adrenoceptor (b2AR) mediates the physiological responses in the airway, which include
bronchodilation, bronchoprotection. The b2-adrenoceptor (b2AR) mediates the physiological
responses in the airway, which include bronchodilation, bronchoprotection, Enhanced
mucociliary clearance.
The b2AR gene is located on chromosome 5q31-q32, a region that is genetically linked to
asthma and related phenotypes. There are three best known polymorphisms in the coding region
of the b2AR gene that can modulate the function of the receptor.
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