Chest Dysphoria in Transmasculine Spectrum Adolescents

Gender Dysphoria Clinical Trial

Official title:

The Effect of Top Surgery on Chest Dysphoria in Assigned-Female-At-Birth, Transmasculine Spectrum Youth and Young Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04195659
• Other study ID #: SP0052757
• Status: Completed
• Start date: October 29, 2019
• Est. completion date: December 31, 2021

Study information

• Verified date: June 2022
• Source: Northwestern University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators hypothesize that masculinizing top surgery (e.g., mastectomy and chest masculinization) leads to an improvement in self-report chest dysphoria, gender dysphoria, and gender congruence in assigned-female-at-birth, transgender and non-binary youth and young adults. This is a prospective, observational study that will enroll assigned-female-at-birth, transmasculine spectrum individuals age 13 to 25 years old who are or are not undergoing top surgery. Participants will complete a set of standard of care questionnaires regarding their chest dysphoria (e.g., distress about the chest), gender dysphoria (e.g., distress about a gender identity that does not match assigned sex), and gender congruence (e.g., degree to which an individual feels they are living in their authentic appearance and gender identity). They will complete this same set of questionnaires either three months after their top surgery or three months after the initial set of surveys.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 81
• Est. completion date: December 31, 2021
• Est. primary completion date: December 31, 2021
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 13 Years to 25 Years

Eligibility

Inclusion Criteria:

• Assigned the female sex at birth
• Affirmed gender identity of male, non-binary, or gender other than female
• English-speaking
• Undergoing top surgery or matches a top surgery participant on age and number of months on testosterone

Exclusion Criteria:

• Non English speaking
• Unable to complete self-report questionnaires

Related Conditions & MeSH terms

• Depressive Disorder, Major
• Gender Dysphoria

Intervention

Procedure:
• Mastectomy and chest masculinization
A surgical procedure in which the breasts are removed and the chest is given a masculine contour.

Locations

Country	Name	City	State
United States	Ann and Robert H Lurie Children's Hospital of Chicago	Chicago	Illinois
United States	Northwestern University	Chicago	Illinois
United States	University of Illinois Chicago	Chicago	Illinois

Sponsors (3)

Lead Sponsor	Collaborator
Northwestern University	Ann and Robert H. Lurie Children's Hospital of Chicago, University of Illinois at Chicago

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Chest Dysphoria	The disruption of individual comfort, physical functioning, and interpersonal relationships from a chest with breasts, as measured by the Chest Dysphoria Measure (Score 0-51, Higher number means greater chest dysphoria)	Three month
Secondary	Gender Dysphoria	Distress about a gender identity that differs from assigned sex, measured by the Utrecht Gender Dysphoria Scale (Score 12-60, Higher number means greater gender dysphoria)	Three month
Secondary	Gender Congruence	Feelings of living in an authentic gender identity and appearance, as measured by the Kozee Transgender Congruence Scale (Score 12-60, Higher number means greater gender congruence)	Three month