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Clinical Trial Summary

The R0 resection rate of gastrointestinal stromal tumor (GIST) with high recurrence risk was relatively low, and the relapse-free survival rate was relatively low, which needed to be further improved. A few retrospective analyses and a small sample of prospective studies have found that neoadjuvant therapy with imatinib mesylate can improve R0 resection rates. Whether neoadjuvant therapy prolongs long-term survival remains unclear. The primary objective of this study was to evaluate 5-year progression-free survival (PFS) for GIST patients with high recurrence risk after neoadjuvant treatment with imatinib mesylate.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04933669
Study type Interventional
Source First Affiliated Hospital of Zhejiang University
Contact Weili Yang, Doctor
Phone +8613989879196
Email yangweili@zju.edu.cn
Status Recruiting
Phase Phase 2
Start date September 7, 2021
Completion date December 31, 2029

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