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Gastrointestinal Perforation clinical trials

View clinical trials related to Gastrointestinal Perforation.

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NCT ID: NCT05226221 Recruiting - Clinical trials for Gastrointestinal Cancer

Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality

GESEMM
Start date: September 1, 2021
Phase:
Study type: Observational

Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality

NCT ID: NCT03053232 Recruiting - Intervention Clinical Trials

Purse String Suture Device vs. Endoclip for Immediate Endoscopic Procedure Associated Gastrointestinal Perforation

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Nowadays, endoscopic techniques have been applied for diagnosing and treating a variety of gastrointestinal diseases, such as endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR)technique for removing early gastrointestinal mucosal cancers. Endoscopic procedure associated gastrointestinal perforation is one of the the most severe complications, which is associated with high morality and needs timely detection and effective treatment in clinical practice.Over 90% procedure associated gastrointestinal perforation occurs immediately within 24 h after endoscopic procedure.Endoclips have been widely used in closing the immediate gastrointestinal perforations, but the location of the endoclips could influence the effective rate, limiting its application. In addition, multiple endoclips should be placed under endoscopy for a relatively large perforation, which could increase the medical cost and the procedure time. At recent, a new purse string suture device (LeoMed, China) has been developed by us and introduced to the clinicalmanagement of such patients with procedure associated gastrointestinal perforations. Clinical data validated that the usage of this new purse string suture in treating immediate procedure associated perforations was greatly convenient and effective with very low reoperation rate and postoperative complication rate. A specially designed loop was equipped in this device, which could be tightened under endoscopy. Thus, compared with the placement of endoclips, this device could be more convenient and effective in completely closing the gastrointestinal perforations.This study will test whether purse string suture device will increase the effectiveness of closingimmediate procedure associated gastrointestinal perforationsunder endoscopyin a randomized controlled trialby comparing the use of purse string suture deviceand endoclips.

NCT ID: NCT01303653 Recruiting - Clinical trials for Gastrointestinal Fistula

Endoscopic Treatment of Intestinal Fistulas and Perforations

Start date: October 2010
Phase: Phase 1
Study type: Interventional

Gastrointestinal leaks or perforations are currently treated through either open or laparoscopic surgical procedures. The purpose of this research is to determine whether new endoscopic tools are safe and effective in the treatment of such conditions and can overcome the need of invasive surgical procedures.