Gastrointestinal Hormones Clinical Trial
Official title:
Impact of Two Genetic Variants of OATP 1B3 or MRP 2 or Rifampin Mediated Transporter Inhibition on Systemic Disposition and Biological Efficacy of CCK-8 in 36 Healthy Male Individuals
The purpose of this study is to evaluate the impact of genetic variants of OATP 1B3 or MRP 2 on the systemic disposition of endogenously formed CCK-8 and to determine the influence of a single-dose of the transporter inhibitor rifampin (600 mg) on the systemic disposition of endogenously formed CCK-8. Endogenous CCK-8 secretion will be induced by a single-dose standardized liquid mixed meal.
n/a
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06022315 -
Impact of Macronutrient Composition of Energy-restricted Diet and Exercise on Body Composition and Appetite Hormones.
|
N/A | |
Completed |
NCT05279183 -
Assessment of Reward Responses to Erythritol Using Flavor Preference Learning
|
N/A | |
Active, not recruiting |
NCT05671965 -
Effects of Oral Xylitol on Subsequent Energy Intake
|
N/A | |
Completed |
NCT04713137 -
Effects of Oral Pre-loads on Subsequent Energy Intake
|
N/A | |
Completed |
NCT00468091 -
Effects of Exendin(9-39) on Gastroduodenal Motility
|
Phase 1 | |
Completed |
NCT04249609 -
Composition of Meals Around Exercise Session
|
N/A | |
Not yet recruiting |
NCT05302206 -
Colonic Glucose vs. Saline Infusion
|
N/A |