Clinical Trials Logo

Clinical Trial Summary

Patients in the intensive care unit (ICU) are often at risk of gastrointestinal dysfunction and malnutrition. Gastrointestinal dysfunction was associated with poor clinical outcomes, including prolonged mechanical ventilation, prolonged ICU stay and increased 90-day mortality. There have been some clinical studies investigating the effects of traditional Chinese acupoint massage, acupuncture, or moxibustion of 7 acupoints (Zhongwan Point (CV12), Tianshu Point (ST25), Qihai Point (CV6), Zusanli point (ST36), Shangjuxu Point (ST37), Neiguan Point (PC6) and Hegu Point (LI4)) on gastrointestinal function recovery. Gastrointestinal dysfunction could be improved by stimulating single acupoint or combining multiple acupoints, and the effects of combined stimulation of multiple acupoints was better for the improvement of gastrointestinal dysfunction. This project aims to study the effects of traditional Chinese acupoint massage, acupuncture, or moxibustion of 7 acupoints (Zhongwan Point (CV12), Tianshu Point (ST25), Qihai Point (CV6), Zusanli point (ST36), Shangjuxu Point (ST37), Neiguan Point (PC6) and Hegu Point (LI4)) on the 28-day survival, and the gastrointestinal function recovery in critically ill patients with with gastrointestinal dysfunction caused by medical diseases and critically ill patients with high risk of malnutrition in ICU, and to observe their effects on the recovery of gastrointestinal barrier function by measuring the serum intestinal fatty acid binding protein (iFABP), citrulline, diamine oxidase (DAO) and D-lactic acid. Studies have shown that serum iFABP, citrulline, DAO and D-lactic acid could reflect the intestinal barrier function of the patients.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06207461
Study type Observational
Source Wuhan Union Hospital, China
Contact
Status Not yet recruiting
Phase
Start date February 15, 2024
Completion date October 1, 2025

See also
  Status Clinical Trial Phase
Completed NCT04901390 - Impact of Yogurt on Gastrointestinal Health, Regularity, and Thoughts N/A
Completed NCT04560595 - Remote Guided Caffeine Reduction N/A
Not yet recruiting NCT05566171 - The Effect of Probiotic Supported Yogurt Consumption on Gastrointestinal Symptoms N/A
Completed NCT04979494 - Association Between SMA Flow and AGI in Critically Ill Patients
Completed NCT04005456 - Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design N/A
Withdrawn NCT02574611 - Use of High Resolution Colonic Manometry in Studying Motility Phase 1
Recruiting NCT04112056 - Post-market Surveillance Study of an Infant Formula Containing Moderately Hydrolyzed Protein and Low Lactose N/A
Completed NCT05765123 - Gastric Emptying Validation Pilot Study (MRI Val)
Active, not recruiting NCT05750433 - Phage 3Determination of Phage/Probiotic Synergistic Effects on Gastrointestinal Health N/A
Not yet recruiting NCT06128785 - Electroacupuncture (EA) Promotes Gastrointestinal Functional Recovery After Radical Colorectal Cancer Surgery N/A
Not yet recruiting NCT04647201 - Study of Biomarkers in Patients of Sepsis Complicated With Gastrointestinal Dysfunction
Completed NCT01828047 - Sublingual Microcirculation and Postoperative Ileus N/A
Completed NCT05309837 - Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects N/A
Not yet recruiting NCT06088940 - The Chemo-Gut Probiotic Trial for Cancer Survivors N/A
Not yet recruiting NCT06376461 - Prospective, Multicentre Study to Validate the GastroIntestinal Dysfunction Score (GIDS) and Describe Prevalence, Outcomes, and Management of Phosphate Disorders in Intensive Care Patients
Completed NCT02486328 - The Effect of Different Sedation Regimes on Cognitive Function in Lower Gastrointestinal System Endoscopy Phase 4
Recruiting NCT05669612 - Promephy - Metabolic Fate of Plant-based Proteins N/A
Completed NCT04187950 - NECTAR Study: Nectar (Honey) Effects on Comfort, Thoughts, and Regularity N/A
Active, not recruiting NCT05418127 - An Efficacy Trial in the Research Area of Gastrointestinal Health & Bloating N/A
Completed NCT04606485 - Does Acupressure Affect Gastrointestinal Function, Pain and Anxiety? N/A