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Gastroesophageal Reflux clinical trials

View clinical trials related to Gastroesophageal Reflux.

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NCT ID: NCT06319521 Not yet recruiting - Clinical trials for Gastroesophageal Reflux Disease

Stellate Ganglion Block on Gastroesophageal Reflux Disease

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: • Can stellate ganglion block improve gastroesophageal reflux symptoms better on the basis of rehabilitation training? Participants will be randomly allocated into the control group or the experimental group, all under rehabilitation treatment, the experimental group will be given Stellate Ganglion Block once a day additionally. The study lasts 20 days for each participant. Researchers will compare the Gastroesophageal Reflux Disease Questionnaire, Pressure pain threshold, Self-Evaluation Questionnaire for Gastroesophageal Reflux Disease, to see if the Stellate Ganglion Block can help improve the symptom.

NCT ID: NCT06317675 Recruiting - Clinical trials for Gastro-oesophageal Reflux Disease

Osteopathic Manipulative Treatment for Gastro-oesophageal Reflux Disease

Start date: February 18, 2024
Phase: Phase 2
Study type: Interventional

To evaluate the effects of osteopathic manipulative treatment in patients affected by symptoms related to gastro-oesophageal reflux disease (GERD)

NCT ID: NCT06316167 Recruiting - Clinical trials for Gastroesophageal Reflux

Mandatory Hiatoplasty in Sleeve Gastrectomy for Gastro-Esophageal Reflux Disease

Start date: March 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to learn about incidence of postoperative gastroesophageal reflux disease in mandatory hiatoplasty performed during gastric sleeve surgery. The main question[s] it aims to answer are: - Incidence of postoperative GERD in patients undergoing gastric sleeve with mandatory hiatoplasty - Comparison of postoperative complication rates, including GERD Participants will answer a follow-up questionnaire, about postoperative quality of life

NCT ID: NCT06304870 Not yet recruiting - Dysphagia Clinical Trials

Impact of Blocking the Glossopharyngeal Nerve on Gastroesophageal Reflux Disease

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore Clinical Effect of Glossopharyngeal Nerve Block on Pharyngeal Dysphagia Induced by Gastroesophageal Reflux Disease. The main question it aims to answer is: • Can Glossopharyngeal Nerve Block improve dysphagia caused by gastroesophageal reflux symptoms on the basis of rehabilitation training? Participants will be randomly allocated into the control group or the experimental group, all under rehabilitation treatment, the experimental group will be given Glossopharyngeal Nerve Block once a day additionally. The study lasts 20 days for each participant. Researchers will compare the Rosenbek penetration-aspiration scale, Gastroesophageal Reflux Disease Questionnaire, Pressure pain threshold, to see if the Glossopharyngeal Nerve Block can help improve the symptom.

NCT ID: NCT06304142 Not yet recruiting - Clinical trials for Gastroesophageal Reflux Disease

Effect of Lidocaine Block on Gastroesophageal Reflux Disease

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: • Can stellate ganglion block improve gastroesophageal reflux symptoms better on the basis of rehabilitation training? Participants will be randomly allocated into the control group or the experimental group, all under rehabilitation treatment, the experimental group will be given Stellate Ganglion Block once a day additionally. The study lasts 10 days for each participant. Researchers will compare the Gastroesophageal Reflux Disease Questionnaire, Pressure pain threshold, Self-Evaluation Questionnaire for Gastroesophageal Reflux Disease, to see if the Stellate Ganglion Block can help improve the symptom.

NCT ID: NCT06280664 Recruiting - Clinical trials for Gastro Esophageal Reflux

Efficacy Of Hiatal Closure For GERD

Start date: October 2, 2020
Phase:
Study type: Observational

The purpose of this protocol is to study the efficacy of hiatal closure for early GERD disease. The study team hypothesizes that hiatal closure for early GERD disease is an efficacious treatment of GERD.

NCT ID: NCT06268548 Recruiting - Clinical trials for Diaphragm Dysfunction

Effect of Manual Diaphragmatic Activation on Diaphragm Function in Patients With Gastroesophageal Reflux Disease

Start date: September 15, 2023
Phase: N/A
Study type: Interventional

This study was conducted to investigate Effect of manual diaphragmatic activation on diaphragm function in patients with gastroesophageal reflux disease

NCT ID: NCT06255886 Not yet recruiting - Clinical trials for Gastroesophageal Reflux

Treatment of Gastroesophageal Reflux Disease in Infants

Start date: June 1, 2024
Phase: Phase 4
Study type: Interventional

Gastroesophageal reflux disease in infants is not fully understood. Infants are prescribed medical treatments that may not be effective or that contribute to adverse side effects and lead to concerns and expenses for the parents and healthcare system. Current guidelines recommend cow-milk-protein free diet as a first-line treatment, but these recommendations are based on weak evidence. This study investigate the efficacy of a cow-milk-protein free diet compared to treatment with a proton pump inhibitor (omeprazole)

NCT ID: NCT06241183 Recruiting - GERD Clinical Trials

Famotidine and Antacids for Treatment of Dyspepsia

Start date: November 9, 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare intravenous famotidine, an H2 receptor antagonist, and Maalox/ Mylanta, an oral antacid, in treatment of dyspepsia in the emergency department. The goal of this study is to reduce patients' pain based on the verbal numerical pain scale. The anticipated outcome is for pain levels in both groups to decrease. It is expected that antacids will improve symptoms more quickly and to a greater degree within an hour of taking medication based on the results of similar studies.

NCT ID: NCT06222177 Recruiting - Clinical trials for Gastro Esophageal Reflux

Thresholds of SLR Maneuver in Obese Patients

SLR obese
Start date: January 1, 2024
Phase:
Study type: Observational

There is an increasing interest in High resolution manometry (HRM) in the preoperative assessment of patients with obesity, in order to identify the best surgical option. Sleeve gastrectomy (SG) has been known to increase the risk of gastro-esophageal reflux disease (GERD). Different techniques have been recently developed and validated to offer to these patients protection against pathologic GERD after SG. A recent study found a significant correlation between straight leg raise (SLR) maneuver during HRM and a positive pH-study. However, these maneuver has not been validated in an obese population, therefore the normality cut-off remain unknown. A multicenter study with a large number of patients undergoing pre-operative assessment for bariatric surgery could provide a precise threshold to predict pathologic esophageal acid exposure time.