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Clinical Trial Summary

This is a phase 1/2 multicenter, open-label umbrella platform study that will evaluate the safety and efficacy of MK-2870 plus paclitaxel versus Ramucirumab plus paclitaxel, for the treatment of participants with advanced or metastatic gastric adenocarcinoma, gastroesophageal junction (GEJ) adenocarcinoma, or esophageal adenocarcinoma who have failed 1 prior line of therapy. This is an estimation study, and no formal hypothesis testing will be performed.


Clinical Trial Description

The master protocol is MK-3475-U06. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06445972
Study type Interventional
Source Merck Sharp & Dohme LLC
Contact
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date July 1, 2024
Completion date October 27, 2028

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