Gastroesophageal Adenocarcinoma Clinical Trial
Official title:
Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial) - a Phase Ib Feasibility Trial
This is a phase 1b prospective, single arm, open-label trial determining the efficacy and feasibility of using a ctDNA assay (test) result to help guide neoadjuvant chemotherapy in subjects with Stage IB, II or Stage III adenocarcinoma of the stomach or gastroesophageal junction (GEA).
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Status | Clinical Trial | Phase | |
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Recruiting |
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A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.
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Phase 1 | |
Completed |
NCT00073502 -
Phase II Study of Single Agent OSI-7904L in Patients With Gastric or Gastroesophageal (GEJ) Cancer
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Phase 2 | |
Recruiting |
NCT04712721 -
Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.
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Early Phase 1 | |
Recruiting |
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Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab
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Phase 1 | |
Withdrawn |
NCT04602117 -
ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer
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Phase 1 | |
Completed |
NCT03794128 -
A Study of Personalized Neoantigen Cancer Vaccines
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Active, not recruiting |
NCT04021108 -
Phase II Study of Short Course FOLFOX Chemotherapy With Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol CA209-76L)
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Phase 2 | |
Not yet recruiting |
NCT06445972 -
Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
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Phase 1/Phase 2 | |
Completed |
NCT01045421 -
MLN8237 in Adults With Nonhematological Malignancies, Followed by MLN8237 in Lung, Breast, Head and Neck or Gastroesophageal Malignancies
|
Phase 1/Phase 2 | |
Completed |
NCT03639714 -
A Study of a Personalized Neoantigen Cancer Vaccine
|
Phase 1/Phase 2 | |
Completed |
NCT01757171 -
Phase II Study of Cabazitaxel in Refractory Metastatic Gastric or Gastroesophageal Adenocarcinoma
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Phase 2 | |
Recruiting |
NCT05152147 -
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers
|
Phase 3 | |
Not yet recruiting |
NCT05986227 -
The Sequential Combination of FOLFOX and Toripalimab for Perioperative Immuno-Oncology Therapy of HER2-negative Adenocarcinoma of the Esophagogastric Junction (Siewert I/II):
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Phase 1/Phase 2 | |
Terminated |
NCT01182610 -
Panitumumab, Paclitaxel, Carboplatin and 5FU in the Treatment of Potentially Resectable Gastroesophageal Adenocarcinoma
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Phase 2 | |
Recruiting |
NCT06043427 -
Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma
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Phase 2 |