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Gastroenteritis clinical trials

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NCT ID: NCT06211621 Completed - COVID-19 Pandemic Clinical Trials

Admission Pattern Among Children With Gastro-intestinal Infections Before and During the Covid-19 Pandemic

Start date: January 2017
Phase:
Study type: Observational

During the Covid-19 pandemic, admission patterns for infections other than Covid-19 have changed dramatically among children worldwide. Particularly admissions due to respiratory infections and later invasive streptococcal infections have been well documented. However, few studies have compared rates af gastro-intestinal infections during the pandemic with the previous years. This study aims to compare the number and characteristics of children hospitalized with gastrointestinal infections before the COVID-19 pandemic, to the first strict lockdown in 2020 and to the second, less strict lockdown in 2021. A retrospective review of medical records will be performed, of patients aged 1 month to 5 years admitted with gastroenteritis at the pediatric department at Slagelse Hospital in Denmark over a period from 2017 to 2021.

NCT ID: NCT06090708 Completed - Clinical trials for Acute Gastroenteritis

Yogurt Probiotic Bacteria on Relieving Young Children Acute Gastroenteritis

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the effect of mothers' application of yogurt probiotic bacteria on relieving their young children's acute gastroenteritis in children had two to five years old. The main hypothesis is children with acute gastroenteritis who receive yogurt probiotic bacteria exhibit less diarrhea, vomiting and dehydration than those who don't.The study subjects were divided into two equal groups (probiotic study group and control group).

NCT ID: NCT05972733 Completed - Gastroenteritis Clinical Trials

Serologic Assay Validation and Proficiency Testing of HIL-214 in Adults

Start date: August 2, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to obtain serum for proficiency testing to confirm assay validity is maintained following the dosing of adults with a pediatric dose of HIL-214.

NCT ID: NCT05439772 Completed - Clinical trials for Inflammatory Bowel Diseases

Examining the Effect of Ondansetron on Bowel Prep Success

Start date: January 1, 2021
Phase: Phase 4
Study type: Interventional

This is a pilot randomized-controlled trial assessing the utility of ondansetron for improving pediatric pre-colonoscopy bowel prep outcomes using the boston bowel preparation score, as well as assessing the impact on patient experience of bowel preparation.

NCT ID: NCT05251909 Completed - Clinical trials for Eosinophilic Gastroenteritis

Efficacy and Safety of Benralizumab in Patients With Eosinophilic Gastritis and/or Gastroenteritis (The HUDSON GI Study)

HUDSON GI
Start date: January 18, 2022
Phase: Phase 3
Study type: Interventional

This is a 3-part study. Part A is randomized, double-blinded, placebo-controlled and includes patients with eosinophilic gastritis and/or duodenal-only disease. After completing Part A, participants can continue to Part C - open-label benralizumab treatment period. Following the decision to close enrollment, patients in both Part A and Part C will be given the option to proceed to 6-months of open-label benralizumab treatment in Part D.

NCT ID: NCT05247879 Completed - Clinical trials for Gastroenteritis Acute

Clinical Effectiveness and Safety of a Novel Oral Rehydration Solution

Start date: June 30, 2022
Phase: N/A
Study type: Interventional

This is a randomised, controlled, open-label study to determine the clinical effectiveness and safety of a novel ORS compared with a commercial ORS in children 1 to 5 years of age attending emergency departments with gastroenteritis.

NCT ID: NCT05076461 Completed - Clinical trials for Acute Gastroenteritis

Ondansetron Versus Domperidone for Treating Vomiting in Acute Gastroenteritis in Children

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Most of the trials conducted comparing ondansetron and domperidone have been conducted among children aged below 5 or 6 years of age while no study from Pakistan has compared efficacy of these antiemetic agents among children up to 12 years of age. The findings of present study will give valuable evidence about the effectiveness of these antiemetic agents to prevent vomiting among children suffering with acute gastroenteritis at a resource limited setting of South Punjab, Pakistan.

NCT ID: NCT04856891 Completed - Clinical trials for Eosinophilic Gastroenteritis

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis

EoDyssey
Start date: May 20, 2021
Phase: Phase 3
Study type: Interventional

This is a Phase 3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult patients with active eosinophilic duodenitis. Subjects who complete the randomized, double-blind, placebo-controlled treatment may have the option to receive 6 doses of open-label lirentelimab (AK002) through the OLE Period of the study.

NCT ID: NCT04819412 Completed - Clinical trials for Rotavirus Gastroenteritis

To Determine the Safety and Efficacy of Liquid ROTAVAC 5C Vaccine Against Childhood Diarrhea Caused by Rotavirus

ROTAVAC5C
Start date: March 20, 2015
Phase: Phase 3
Study type: Interventional

Study Rationale A single Rotavirus vaccine container with the vaccine virus and antacid buffer would be ideal for logistical, administrative and distribution ease, especially in routine immunization program. - The advantages of the liquid vaccines are: Liquid vaccines take lesser time to administer compared to the current practice of giving antacid buffer prior to vaccine which takes 40% more time to administer. - Easier to transport as it is stable at 2-80C compared to the frozen formulation that needs to be stored at -200C and transported in dry ice. - Chances of human error during administration are lesser than the sequential administration of antacid and vaccine.

NCT ID: NCT04682860 Completed - Abdominal Pain Clinical Trials

Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide

Start date: September 8, 2021
Phase: Phase 4
Study type: Interventional

One of the most common complaints of admission to the emergency room is gastroenteritis. One of the most common complaints in acute gastroenteritis is abdominal pain. The aim of our study is to investigate whether hyoscine butylbromide used within the indication has an effect on abdominal pain due to acute gastroenteritis. The main purpose of our study is to reduce the pain of the patient at 30th and 60th minutes compared to 0th minute.